Results 71 to 80 of about 311,209 (306)

Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]

open access: yes, 2018
This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau   +3 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Novel copper-containing ferrite nanoparticles exert lethality to MRSA by disrupting MRSA cell membrane permeability, depleting intracellular iron ions, and upregulating ROS levels

open access: yesFrontiers in Microbiology, 2023
ObjectiveThe widespread use of antibiotics has inevitably led to the emergence of multidrug-resistant bacterial strains, such as methicillin-resistant Staphylococcus aureus (MRSA), making treatment of this infection a serious challenge.
Jinhua Ye   +11 more
doaj   +1 more source

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones [PDF]

open access: yes, 2016
Our previous paper (Wilkinson et al, 2016) used high-resolution cryo-electron microscopy to solve the structure of the Escherichia coli RecBCD complex, which acts in both the repair of double-stranded DNA breaks and the degradation of bacteriophage DNA ...
Aedo   +44 more
core   +5 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

The Antibacterial Activity and Mechanism of Action of Luteolin Against Trueperella pyogenes

open access: yesInfection and Drug Resistance, 2020
Yuru Guo,1 Yan Liu,2 Zehui Zhang,1 Menghan Chen,1 Dexian Zhang,1 Chunlian Tian,1 Mingchun Liu,1 Guotuo Jiang2 1Key Laboratory of Livestock Infectious Diseases in Northeast China, Ministry of Education, College of Animal Science and Veterinary Medicine ...
Guo Y   +7 more
doaj  

The Antibacterial Mechanism of Ozone Water Combined with Lactobacillus paracasei Z21 on E.coli O157:H7 in Mung Bean Sprouts

open access: yesShipin gongye ke-ji, 2022
To explore the bactericidal effect, cell structure and biofilm removal mechanism of ozone water combined with Lactobacillus paracasei Z21 fermented supernatant on E.
Xinmin MA   +6 more
doaj   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

open access: yesAdvanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti   +5 more
wiley   +1 more source

Progress in antibacterial applications of nanozymes

open access: yesFrontiers in Chemistry
Bacterial infections are a growing problem, and antibiotic drugs can be widely used to fight bacterial infections. However, the overuse of antibiotics and the evolution of bacteria have led to the emergence of drug-resistant bacteria, severely reducing ...
Keyuan Zhao   +4 more
doaj   +1 more source

Proderm technology: a water- based lipid delivery system for dermatitis that penetrates viable epidermis and has antibacterial effects. [PDF]

open access: yes, 2019
BackgroundA defective skin barrier and bacterial colonization are two important factors in maintenance and progression of atopic dermatitis and chronic allergic/irritant hand dermatitis.
Caputo-Janhager, Melinda   +4 more
core   +3 more sources

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