Results 51 to 60 of about 889,789 (245)

El problema de la fugida de l'anastomosi : antibiòtics en cirurgia colorectal [PDF]

open access: yes, 2007
Les operacions quirúrgiques colorectals (en les quals s'intervé sobre el colon, el recte o ambdós) poden presentar complicacions. Una d'aquestes complicacions és la fugida de l'anastomosi, la unió que es fa entre els extrems que han quedat oberts després
Oller Sales, Benjamín
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Resistance to antibiotics [PDF]

open access: yesMedicamentul Veterinar, 2007
The antibiotics represent the most important therapeutic arsenal in the fight against pathogen microorganisms. Even in the beginning of their use, there was registered bacterial resistance, phenomenon thatbecame an alarming subject in the last decades ...
Oros N.A.,   +4 more
doaj  

Health Economics of Antibiotics

open access: yesPharmaceuticals, 2010
Antibiotics have made a significant contribution to improving patient health, but policy makers and health care payers are concerned about the costs of antibiotics in addition to their effectiveness.
Steven Simoens
doaj   +1 more source

Formigues que fabriquen els seus antibiòtics [PDF]

open access: yes, 2017
Des de la descoberta dels antibiòtics per Alexander Fleming el 1928, aquestes substàncies han salvat moltes vides arreu del món. Tanmateix, cada cop hi ha més microorganismes infecciosos que n'esdevenen resistents.
Bueno i Torrens, David, 1965-
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Nanotech meets antibiotics: nucleotide antibiotics delivered by lipid nanoparticles

open access: yesFrontiers in Cellular and Infection Microbiology
The global spread of multidrug-resistant bacteria poses a serious challenge to effective therapy and public health. The rising resistance to small-molecule antibiotics underscores the limitations of conventional antimicrobial strategies and highlights ...
Bookun Kim   +3 more
doaj   +1 more source

Resistències als antibiòtics La responsabilitat del Veterinari en l'aparició i la prevenció [PDF]

open access: yes, 2011
Treball presentat a l'assignatura de Deontologia i Veterinària Legal ...
Cantavella Corredor, Jana   +1 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Macròlids: mecanismes d'acció i de resistència [PDF]

open access: yes, 2005
Els macròlids són agents descrits per primera vegada als anys cinquanta, molt emprats en el tractament de microorganismes grampositius. Actuen al ribosoma, unint-se de manera reversible a la subunitat 50S. Actualment se'n coneixen diferents mecanismes de
Portillo, Aránzazu   +2 more
core  

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