Results 61 to 70 of about 889,789 (245)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Dispensació d'antibiòtics sense recepta a les oficines de farmàcia [PDF]

, 2014
Introducció: L'ús indiscriminat d'antibiòtics, l'augment de les resistències i la mancança d'investigació en nous antibiòtics fa que ens trobem en un moment de crisi antibiòtica on cal prendre ...
Guinovart i Moncunill, Maria Candela, Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia, Universitat Autònoma de Barcelona. Facultat de Medicina   +2 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Detecció d'antibiòtics en el vacú lleter [PDF]

, 2013
Treball presentat a l'assignatura de Deontologia i Veterinària Legal ...
Pastor Ripoll, Aida, Remolar Franch, Pere, Toneu Domènech, Laia   +2 more
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Influència de l'ètnia en el comportament farmacocinètic dels antibiòtics [PDF]

, 2014
Un estudi retrospectiu realitzat a l'Hospital del Mar ha investigat la relació entre l'antibiòtic amikacina i l'ètnia dels pacients tractats amb ell entre gener de 2003 i desembre de 2010.
Barrantes-González, Melisa, Grau Cerrato, Santiago   +1 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Management Standard on Perioperative Prophylactic Use of Antibiotics in Peking Union Medical College Hospital (2023)

Xiehe Yixue Zazhi
To standardize the use of antibiotics for surgical prophylaxis, ensure patient safety, improve medical quality, and combat bacterial resistance, the editorial committee at Peking Union Medical College Hospital for the management of antibiotics for ...
Editorial Committee on Management Standard on Perioperative Prophylactic Use of Antibiotics in Peking Union Medical College Hospital
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Els bacteris escampen la resistència indiscriminada als antibiòtics [PDF]

, 2009
La pertorbació de la replicació de material genètic dels bacteris indueix una resposta cel·lular (anomenada SOS) que genera la reordenació dels seus cromosomes i la captació, l'expansió i l'expressió d'una família d'elements genètics mòbils, coneguts com
Barbé García, Jordi
core   +1 more source