Results 91 to 100 of about 15,007 (187)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

AKTIVITAS ANTIBAKTERI DAN ANTIBIOFILM DARI EKSTRAK DAUN BANGUN-BANGUN (Coleus amboinicus L.) TERHADAP BAKTERI Staphylococcus aureus

JIIS: Jurnal Ilmiah Ibnu Sina
Pembentukan biofilm oleh bakteri khususnya genus Staphylococcus menjadi permasalahan kesehatan yang cukup serius. Berbagai tanaman obat telah digunakan untuk mengendalikan infeksinya, namun belum ada penelitian terkait aktivitas antibiofilm dari Coleus ...
Fitra Romadhonsyah, Aisha Nanda Caela Amry, Annisa Fitria, Arde Toga Nugraha, Arba Pramundita Ramadani, Nangim Khasanah   +5 more
doaj   +1 more source

Rhamnolipid Micelles Assist Azithromycin in Efficiently Disrupting Staphylococcus aureus Biofilms and Impeding Their Re-Formation

International Journal of Nanomedicine, 2023
Shiyu Lin,* Xiaojuan Li,* Yuning Zhang,* Wei Zhang, Gang Shu, Haohuan Li, Funeng Xu, Juchun Lin, Hualin Fu Innovative Engineering Research Center of Veterinary Pharmaceutics, Department of Pharmacy, College of Veterinary Medicine, Sichuan ...
Lin S, Li X, Zhang Y, Zhang W, Shu G, Li H, Xu F, Lin J, Fu H   +8 more
doaj  

Auranofin Releasing Antibacterial and Antibiofilm Polyurethane Intravascular Catheter Coatings

Frontiers in Cellular and Infection Microbiology, 2019
Intravascular catheter related bloodstream infections (CRBSIs) are a leading cause of hospital-acquired infections worldwide, resulting not only in the burden of cost and morbidity for patients but also in the over-consumption of medical resources for ...
Hanyang Liu, Shashank Shukla, Noel Vera-González, Nagendran Tharmalingam, Eleftherios Mylonakis, Beth Burgwyn Fuchs, Anita Shukla   +6 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

PEMANFAATAN ULANG PELEPAH KELAPA SAWIT (Elaeis guineensis) UNTUK APLIKASI BIOMEDIS MELALUI UJI IN VITRO ANTIBAKTERI, ANTIBIOFILM, DAN ANTIOKSIDAN

JIIS: Jurnal Ilmiah Ibnu Sina
Pelepah Elaeis guineensis memiliki banyak manfaat farmakologis yang dapat dikembangkan, terutama sebagai antibiofilm dan antioksidan. Studi sebelumnya menunjukkan bahwa E.
Deni Setiawan, Samsul Hadi, Nurul Mardiati, Nashrul Wathan, Hilma Aulia, Siti Najwa, Muhammad Rasyid Ridha, Moch. Saiful Bachri   +7 more
doaj   +1 more source

RAFT Copolymerization of DMAEA and AETAC Toward Charge‐Shifting Copolymers With Tunable Heparin Complexation

Macromolecular Rapid Communications, EarlyView.
Copolymers based on charge‐shifting (DMAEA) and permanently charged (AETAC) cationic acrylates were copolymerized via the RAFT process to achieve polycations with well‐defined composition. Moderate content of AETAC did not affect hydrolysis rates but significantly enhanced heparin binding.
Radoslava Sivkova, Monika Matiyani, Andrii Mahun, Volodymyr Lobaz, Gabriela Sarahí García‐Briones, Dana Kubies   +5 more
wiley   +1 more source

Modular Polymers With Tuneable Charge and Amphiphilicity for Effective Antimicrobial Photodynamic Therapy

Macromolecular Rapid Communications, EarlyView.
A modular dual‐strategy platform combining free radical copolymerisation and post‐polymerisation modification yields a library of ruthenium‐functionalised polymers for antimicrobial photodynamic therapy. Tuneable composition and net charge govern activity against multidrug‐resistant Pseudomonas aeruginosa biofilms and Staphylococcus aureus under ...
Ali Balasini, Jannik Fryn, Margaux Bonnardot, Jérémy Godard, Tristan Montier, Gilles Lemercier, Franck Thétiot, Tony Le Gall, Ulrich Jonas   +8 more
wiley   +1 more source

Antibiofilm activities of compounds from natural sources / Muhamad Safwan Razali [PDF]

, 2021
In nature, some bacteria have the ability to produce biofilm which acts as a protective barrier against antibiotic killings. When bacteria produce biofilm, they are found to be more resistant against host defense mechanisms as compared to their ...
Razali, Muhamad Safwan
core  

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source