Results 161 to 170 of about 15,007 (187)

Mitochondrial CLPP in Health and Disease: Mechanisms, Therapeutic Duality and Emerging Opportunities

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
The graphical abstract illustrates the context‐dependent therapeutic modulation of CLPP. Pharmacological CLPP activation has reached clinical application in cancer (black arrow), whereas reduced CLPP activity has shown beneficial effects experimentally in models of primary mitochondrial disease and metabolic syndrome, as well as cancer (grey arrows ...
Lea Isermann, Aleksandra Trifunovic
wiley   +1 more source

Differential Expression of Human and Bacterial Proteins Reveals Microbiome–Host Crosstalk in Metabolic Disorders

PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT Purpose The growing prevalence of obesity, MetS, and T2DM highlights the need to better understand host–microbiota interactions. While gut microbiota has been widely investigated, interactions between the oral microbiota and human salivary proteins remain largely unexplored.
Carlos Vinicius Ferreira da Silva, Carlos José Ferreira da Silva, Fernanda da Silva Marinho, Youssef Bacila Sade, Sandra Mara Naressi Scapin, Fabiano L. Thompson, Cristiane Thompson, Eidy de Oliveira Santos   +7 more
wiley   +1 more source

Gold Nanoparticles Coated With the Antimicrobial Peptide Os‐C(W5): Anticandidal and Biological Activity

Journal of Peptide Science, Volume 32, Issue 9, September 2026.
Gold nanoparticles conjugated with a tick‐derived antimicrobial peptide, Os‐C(W5), demonstrate enhanced proteolytic stability and potent antifungal activity against Candida albicans biofilms and planktonic cells. These non‐cytotoxic nanoconjugates represent a promising biocompatible strategy for combating resistant fungal infections while maintaining ...
P. J. Palm, R. R. Chirombo, C. K. Chiramba, J. C. Serem, H. Taute, M. van der Walt, A. R. M. Gaspar, M. J. Bester   +7 more
wiley   +1 more source

Laser‐Patterned Antibacterial Microgrids With Silver Nanoparticles for Autonomous Sterilization on Public Escalator Belts

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT The past few decades have witnessed multiple outbreaks of pandemics. Hygiene in public facilities is one of the key factors in maintaining public health security. Escalator belts, as frequently touched by passengers, become a potential medium for spreading pathogens.
Yang Xu, Yee Him Timothy Chan, Xupeng Lu, Ruohan Yu, Yexin Pan, Siyu Chen, Haosong Zhong, Le Jing, Cuiyun Yang, Yangyi Huang, Yi Chen, Minseong Kim, Mitch Guijun Li   +12 more
wiley   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, Volume 26, Issue 9, September 2026.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Nanotechnology‐Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano‐immunostimulants improve fish health through targeted and controlled delivery of immunostimulatory compounds. Biodegradable polymeric and lipid‐based nanocarriers enhance immune responses, bioavailability and disease resistance while reducing antibiotic dependence and environmental impact.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

A Lytic Bacteriophage Cocktail Attenuates Carbapenem‐Resistant Klebsiella pneumoniae–Acinetobacter baumannii Mixed‐Species Biofilms and Reshapes Transcriptional Responses

Microbial Biotechnology, Volume 19, Issue 9, September 2026.
A lytic phage cocktail targeting CRKP–CRAB mixed biofilms was systematically evaluated through in vitro, device‐associated, and in vivo models. Integrated transcriptomic analysis revealed molecular responses underlying biofilm disruption, providing mechanistic insights and experimental evidence supporting phage cocktails as a promising strategy against
Xuefang Ren, Rui Zhu, Yijiang Yang, Xiaojuan You, Liuxiang Wang, Guangyu Fu, Yehuan Zheng, Chunxia Wang, Zhentao Wang, Yongwei Li   +9 more
wiley   +1 more source

Mechanistic Investigations of a Novel Lactam Antifungal Agent Against Candida albicans

APMIS, Volume 134, Issue 9, September 2026.
ABSTRACT Candida albicans presents a major, yet underestimated challenge in clinical settings due to its increased resistance to treatment. This study intended to focus on the utility of a novel proprietary lactam molecule, a quorum sensing (QS) inhibitor, against C. albicans. We assessed isolate susceptibility to lactam treatment. In addition, RNA‐Seq
Hafsa Abduljalil, William Johnston, Mark Butcher, Neil Parry, Joanne O'Keeffe, Yvonne Davies, Gordon Ramage   +6 more
wiley   +1 more source

Antimicrobial, Antibiofilm and Toxicological Assessment of Propolis [PDF]

Antibiotics, 2023
Antimicrobial resistance is a serious problem for the control of infections and infectious diseases. Propolis is a substance produced by honeybees with antimicrobial and antibiofilm properties.
Celia M Antunes, Maria Cristina Queiroga, Marta Laranjo   +2 more
exaly   +2 more sources

Antibiofilm Effect of Cinnamaldehyde-Chitosan Nanoparticles against the Biofilm of Staphylococcus aureus

Antibiotics, 2022
Food contamination caused by food-spoilage bacteria and pathogenic bacteria seriously affects public health. Staphylococcus aureus is a typical foodborne pathogen which easily forms biofilm. Once biofilm is formed, it is difficult to remove.
Yulong Tan
exaly   +2 more sources