Results 161 to 170 of about 5,783,774 (194)

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, Volume 13, Issue 51, 14 September 2026.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, Volume 13, Issue 52, 18 September 2026.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

A Synergistic Nanotherapeutic Platform Leveraging Bioorthogonal Amplification and Ultrasound Triggering for Multidrug‐Resistant Bacterial Clearance and Wound Repair

Aggregate, Volume 7, Issue 9, September 2026.
Bioorthogonal targeting directs an ultrasound (US)‑responsive Mn‑cyanine nanoplatform to methicillin‐resistant Staphylococcus aureus, where US triggers simultaneous hydroxyl radical generation and CO release. This synergistic sonodynamic/gas therapy eradicates bacteria and biofilms, accelerates wound healing (99.1% closure in 10 days), and avoids ...
Wentao Lei, Binbin Fu, Cuizhou Luan, Jinhao Li, Sijia Huang, Jianping Shao, Zifei Wang, Shufen Ye, Zhengyin Pan, Liang He   +9 more
wiley   +1 more source

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 956-967, September 2026.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, Volume 4, Issue 3, September 2026.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Antibacterial and Antibiofilm Activity of a Chemically Characterized Cinnamomum verum Bark Methanolic Extract Against Multidrug‐Resistant Bacteria: Preliminary Antibiotic–Interaction Screening and Exploratory Molecular Docking

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri, Sarra Elmsehli, Assia kenich, Mabrouk Horchani, Hanen Najjaa, Naima Najah, Hasan Aljohi, Mohammad Nasser Alkhrayef, Roberta Ascrizzi, Guido Flamini, Ibrahim O. Alanazi, Mozaniel Santana de Oliveira   +11 more
wiley   +1 more source

Comparative Phytochemical and Biological Evaluation of Four Thymus Species From Türkiye for Dermocosmetic Applications

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Four Thymus species from Anatolia are profiled through molecular networking and multi‐target bioassays across skin‐relevant cellular models. Triterpene‐rich extracts inhibit key anti‐aging enzymes and promote wound closure in fibroblast, keratinocyte, and endothelial cells.
Ebru Özdemir Nath, Pierre‐Eric Campos, Audrey Le Cabec, Gül İpek Gündoğan, Diren Ergin, Ahsen Çetin, Sefa Sönmez, Emilie Destandau   +7 more
wiley   +1 more source

Clean Synthesis of N‐4‐Alkylamino‐7‐chloroquinoline Cyclic Imides: Influence of Lipophilicity on Antibacterial and Ecotoxicological Properties

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
For series 2a–d, there appears to be optimal activity against Klebsiella pneumoniae when lipophilicity is intermediate (log P 2.64 for 2b). Similarly, for series 2e–g, activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus mutans also increases (log P 3.71 for 2f).
Agenor P. Luz‐Filho, Thais C. Silva, Matheus B. Silva, Abraão P. Sousa, Helivaldo D. S. Souza, Priscila S. V. Lima, Alexandre Almeida‐Júnior, Fábio C. Sampaio, Petrônio F. Athayde‐Filho, Gabriela F. Fiss   +9 more
wiley   +1 more source

GC‐MS Analyses and Bioactivity Evaluation of Origanum minutiflorum Essential Oil: Antioxidant, Antibacterial, Genotoxicity, and Molecular Docking Studies

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
GC–MS analysis reveals the chemical composition of Origanum minutiflorum essential oil, while biological and computational investigations demonstrate its antioxidant, antibacterial, and genotoxic properties. Favorable ADME profiles and molecular interactions of the major terpenoids highlight their potential as natural antibacterial agents and promising
Derya Efe, Ayça Aktaş Karaçelik, Sedat Bozarı, Gözde Yalçın Özkat, Büşra Korkmaz   +4 more
wiley   +1 more source

Natural Lactone‐Based Quorum Sensing Inhibitors Attenuate Virulence in Pseudomonas aeruginosa

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Targeting bacterial communication, lab‐generated lactones (Lx) inhibited biofilm formation and eliminated mature biofilms within 24–48 h. Lx treatment also suppressed pyocyanin and rhamnolipid production while downregulating rhlR expression, highlighting their promise as potent quorum‐sensing (QS) inhibitors and next‐generation antibiofilm therapeutics.
Shivani Chaturvedi, Ashutosh Sharma, Tanisha Singh, Bibhuti Bhusan Das, Tanmay Dutta, Sunil Kumar Khare   +5 more
wiley   +1 more source