Results 71 to 80 of about 5,783,774 (194)

Antibiofilm Activity of Essential Clove Oil Against Biofilm Forming Bacteria

, 2022
Samples were collected from mouth by swabbing across the gingival and subgingival region, as well as from the roof and floor of the buccal cavity from individuals.
Bharti Ghude Wadekar and Komal Deviprasad Bernwal
core   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Impact of Pseudomonas aeruginosa biofilm exopolysaccharide composition on bacteriophage and bacteriophage-antibiotic combination activity

Antimicrobial Agents and Chemotherapy
Multidrug-resistant Pseudomonas aeruginosa is a leading cause of hospital-acquired infections, including medical device infections, partially due to the organism’s ability to produce biofilm on prosthetic material.
Sean R. Van Helden, Callan R. Bleick, Dana J. Holger, Amer El Ghali, Jose Alexander, Keith S. Kaye, Steven H. Marshall, Laura J. Rojas, Robert A. Bonomo, Susan M. Lehman, Michael J. Rybak   +10 more
doaj   +1 more source

Antibacterial and Antibiofilm Activity of Endophytic Alternaria sp. Isolated from Eremophila longifolia

, 2023
The threat to public health resulting from the emergence of antimicrobial resistance (AMR) is ever rising. One of the major bacterial pathogens at the forefront of this problem is methicillin-resistant Staphylococcus aureus, or MRSA, for which there is a
Simon E. Moulton, Enzo A. Palombo, Bita Zaferanloo, Peter J. Duggan, Daniel J. Caruso   +4 more
core   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Antibacterial and antibiofilm activity of a triterpenoid-rich Eucalyptus globulus leaf extract against gram-positive bacteria

Scientific Reports
Eucalyptus globulus leaf extract (EGL) is a phytocomplex associated with antimicrobial and anti-inflammatory effects, but a comprehensive characterization of its chemical composition and its relationship with biological activity remains limited.
Chiara Spaggiari, Costanza Spadini, Laura Righetti, Nicolò Mezzasalma, Alessandro Cupola, Marco Pieroni, Giannamaria Annunziato, Clotilde Silvia Cabassi, Gabriele Costantino   +8 more
doaj   +1 more source

Antibiofilm Activity and Synergistic Effects of Thymol-Loaded Poly (Lactic-Co-Glycolic Acid) Nanoparticles with Amikacin against Four Salmonella enterica Serovars

Canadian Journal of Infectious Diseases and Medical Microbiology, 2023
Background. Salmonella species are frequently linked to biofilm-associated infections. Biofilm formation intensively reduces the efficacy of antibiotics and the host immune system. Therefore, new therapeutic strategies are needed.
Christian Ramsès Kuaté Tokam, Borel Bisso Ndezo, Nathalie Boulens, Eric Allémann, Florence Delie, Jean Paul Dzoyem   +5 more
doaj   +1 more source

Antibiofilm Activity of Three Essential Oils Against ESBL-Producing Klebsiella pneumoniae: An In Vitro and In Silico Investigation of Putative Molecular Targets

Biofilm formation is a major contributor to antibiotic resistance in Klebsiella pneumoniae, posing a serious challenge to current therapeutic strategies.
Karim Houali, Fares Rekbi, Hillal Sebbane, Sulaiman Abdullah Ali Alsalamah, Hakim Belkhalfa, Souad Lahcene, Idir Moualek, Mohammed Saad Aleissa, Assia Derguini, Nosiba S. Basher, Nasir A. Ibrahim, Bilal Saoudi, Karim Bariz, Lamia Trabelsi   +13 more
core   +1 more source

Antibiofilm activity of aminopropanol derivatives against Pseudomonas aeruginosa [PDF]

, 2018
Bacterial biofilm, particularly formed by Pseudomonas aeruginosa, are a cause of severe chronic infectious diseases. Bacteria within a biofilm are phenotypically more resistant to antibiotics and the macroorganism immune system, making it an important ...
D. M. Dudikova, M. L. Dronova, V. V. Nedashkivska, N. O. Vrynchanu, Z. S. Suvorova, A. O. Sharova   +5 more
core   +1 more source

The Antimicrobial Peptide AMP-17 Derived from Musca domestica Inhibits Biofilm Formation and Eradicates Mature Biofilm in Candida albicans

, 2022
The biofilm formation of C. albicans represents a major virulence factor during candidiasis. Biofilm-mediated drug resistance has necessitated the search for a new antifungal treatment strategy.
Chaoqin Sun, Longbing Yang, Zhou, Luoxiong, Zhao, Xinyu, Guo Guo, Tian, Chunren, Zhenglong Jiao, Yang, Longbing, Jiao, Zhenglong, Sun, Chaoqin, Huang, Mingjiao, Xinyu Zhao, Mingjiao Huang, Luoxiong Zhou, Guo, Guo, Jian Peng, Chunren Tian, Peng, Jian   +17 more
core   +1 more source