Results 71 to 80 of about 21,393 (200)

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Development and Evaluation of Biogenic Nano-Hydrogel Incorporating Silver Nanoparticles for Wound Healing and Antibiofilm Activity

Wound healing is a complex, multi-phase process involving numerous cellular and molecular mechanisms. Chronic wounds, exacerbated by conditions such as diabetes or bacterial biofilms, pose significant clinical challenges, increasing healthcare costs ...
J. Sarada, S. Anju
core   +1 more source

Antimicrobial and anti-biofilm activity of Hypericum brasiliense extract and its fractions on Staphylococcus of canine origin

Scientific Reports
The growing resistance to antimicrobials, partly due to the ability to form biofilms, poses a challenge for developing new antimicrobial agents. This study assessed the antimicrobial and antibiofilm activity of Hypericum brasiliense extract, Japonicin ...
Yasmim de M. Assumpção, Lialyz S. P. Andre, Izabel M. Teixeira, Carolina O. da Fonseca, Francisco P. Machado, Tainara A. N. Ribeiro, Renata F. A. Pereira, Daniela Sachs, Leandro M. Rocha, Bruno Penna   +9 more
doaj   +1 more source

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Antibiofilm Activity of Plant Polyphenols

, 2016
In the history of human medicine, antibiotics represent epochal examples of medical progress. However, with an approaching antibiotic crisis due to the emergence and extensive spread of antimicrobial resistance among bacterial agents, as well as to ...
Pavel Mučaji, Silvia Fialová, Lívia Slobodníková, Katarína Rendeková, Ján Kováč   +4 more
core   +1 more source

Synergistic Potentiation of Antimicrobial and Antibiofilm Activities of Penicillin and Bacitracin by Octyl Gallate, a Food-Grade Antioxidant, in Staphylococcus epidermidis

, 2022
Staphylococcus epidermidis is a major nosocomial pathogen that frequently forms biofilms on indwelling medical devices. This study aimed to investigate the synergistic antimicrobial and antibiofilm activities of octyl gallate (OG) in combination with ...
Ji, Yinduo, Yinduo Ji, Santativongchai, Pitchaya, Jeon, Byeonghwa, Phitsanu Tulayakul, Tulayakul, Phitsanu, Byeonghwa Jeon, Pitchaya Santativongchai   +7 more
core   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Antimicrobial and antibiofilm activity of Cymbopogon flexuosus essential oil microemulsions

, 2019
The objective of the study was to determine the antimicrobial activity antibiofilm and to identify the main components of the essential oil (EO) obtained from the leaves of Cymbopogon flexuosus.
Renata Moura (7855802), Alessandra F. Millezi (7855805), Karine Angélica Dalla Costa (6327293)   +2 more
core   +1 more source

Antifungal and Antibiofilm Activity of Riparin III against Dermatophytes

, 2023
The ability of dermatophytes to develop biofilms is possibly involved in therapeutic failure because biofilms impair drug effectiveness in the infected tissues. Research to find new drugs with antibiofilm activity against dermatophytes is crucial.
Marcelo Antônio Nóbrega da Rocha, Juliana Moura-Mendes, José Maria Barbosa-Filho, Gabriela Ribeiro de Sousa, Edeltrudes de Oliveira Lima, Jailton de Souza-Ferrari, Emanuel Pereira Silva, Fillipe de Oliveira Pereira, Risley Nikael Medeiros Silva   +8 more
core   +1 more source

A narrow bandgap Schottky heterojunction Fe2N/CeO2 microneedle triggering sonodynamic reactive oxygen species storm for drug‐resistance‐free skin fungal infection

BMEMat, EarlyView.
Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang, Jiayi Yang, Ning Tang, Youbin Zheng, Yichao Hou, Chutong Liu, Lihao Guo, Yingying Liao, Gandong Zhou, Weiwei Wu, Xin Du, Shuxiang Xu, Jie Yin, Miaomiao Yuan   +13 more
wiley   +1 more source