Results 121 to 130 of about 310,627 (310)

Resistance to carbapenems in non-typhoidal Salmonella enterica serovars from humans, animals and food [PDF]

, 2018
Non-typhoidal serovars of Salmonella enterica (NTS) are a leading cause of food-borne disease in animals and humans worldwide. Like other zoonotic bacteria, NTS have the potential to act as reservoirs and vehicles for the transmission of antimicrobial ...
Fernández, J., Guerra, B., Rodicio Rodicio, María del Rosario   +2 more
core   +3 more sources

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Bacteroides fragilis Protects Against Antibiotic-Associated Diarrhea in Rats by Modulating Intestinal Defenses

Frontiers in Immunology, 2018
Antibiotic-associated diarrhea (AAD) is iatrogenic diarrhea characterized by disruption of the gut microbiota. Probiotics are routinely used to treat AAD in clinical practice; however, the effectiveness and mechanisms by which probiotics alleviate ...
Wendi Zhang, Bo Zhu, Jiahui Xu, Yangyang Liu, Enqi Qiu, Zhijun Li, Zhengchao Li, Yan He, Hongwei Zhou, Yang Bai, Fachao Zhi   +10 more
semanticscholar   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

Experimental infection of newly weaned pigs with human and porcine strains of Serpulina pilosicoli [PDF]

, 1996
Cultures of Serpulina pilosicoli 95/1000, isolated from a pig with porcine intestinal spirochetosis (PIS), and S. pilosicoli WesB, isolated from an Aboriginal child with diarrhea, were used to infect 5-week-old newly weaned pigs. Four of 12 pigs infected
Trott, D.J., Huxtable, C.R., Hampson, D.J.   +2 more
core   +1 more source

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

Nucleoside‐Based Hydrogel Platform Synergizes with Photothermal Effects for Enhanced Biofilm Eradication Against Periodontitis

Advanced Science, EarlyView.
A synergistic antibiofilm hydrogel platform (ZBAg@FNP) is developed by encapsulating an organic small‐molecule photothermal agent (FNP) within a silver ion‐mediated supramolecular hydrogel (ZBAg), enabling photothermal disruption of biofilm integrity and controlled Ag⁺ ion release upon irradiation.
Yinghui Wen, Yunfei Li, Tiannan Liu, Chongkui Sun, Hang Zhao, Yao Yuan, Shiping Yang, Tingxing Zhao, Jiang Liu   +8 more
wiley   +1 more source

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

CLOSTRIDIUM DIFFICILE-ASSOCIATED DIARRHEA (LITERATURE REVIEW)

Сибирский онкологический журнал, 2016
Significance of C. difficile and A/B toxins produced by this bacteria was shown in the literature review on antibiotic-associated diarrhea. Problems concerning epidemiology, clinical symptomatology, complications from this disease, diagnostics as well as
N. V. Dmitrieva, I. А. Klyuchnikova, I. I. Shilnikova   +2 more
doaj  

Perceptions of fecal microbiota transplantation for Clostridium difficile infection: factors that predict acceptance. [PDF]

, 2016
BackgroundDespite the effectiveness of fecal microbiota transplantation (FMT) for treating recurrent Clostridium difficile (C. difficile) infection, some patients are reluctant to accept this therapy.
Chen, Lea Ann, Hirsh, Jacqueline, Malter, Lisa, Mone, Anjali, Park, Leslie, Poles, Michael A, Price, Jennifer C, Tzimas, Demetrios   +7 more
core   +1 more source