Results 191 to 200 of about 310,627 (310)

Intact pulse cotyledon cell diet improves systemic growth via the somatotropic axis in malnourished mice

open access: yesiMetaOmics, EarlyView.
The MAL‐IC diet promotes growth in malnourished mice by regulating the gut microbiota—increasing the abundance of carbohydrate‐utilizing bacteria and SCFAs production. SCFAs circulate to the liver via the gut–liver axis, where they bind FFAR2 and activate the somatotropic axis, thereby stimulating GHR‐mediated GH signaling and increasing IGF‐1 and ...
Yumeng Yan   +5 more
wiley   +1 more source

Akkermansia muciniphila enhances chicken resistance to infectious bronchitis virus by boosting GABA synthesis and suppressing the NF‐κB inflammatory pathway

open access: yesiMetaOmics, EarlyView.
Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng   +22 more
wiley   +1 more source

Inhibition of ferroptosis by microbiota‐derived lithocholic acid underlies the intestinal radioprotection of a host defensin‐derived oligopeptide

open access: yesiMeta, EarlyView.
AT9(C/G), an oligopeptide derived from human defensin 5, enriches Bifidobacterium pseudolongum and increases lithocholic acid (LCA) levels in the intestine. Reduced levels of LCA link to increased severity of ionizing radiation‐induced intestinal injury (IRIII) in both murine and clinical studies.
Xue Ouyang   +16 more
wiley   +1 more source

Development of a patient/proxy-reported instrument for pediatric antibiotic-associated diarrhea. [PDF]

open access: yesPLoS One
Ardestani SK   +5 more
europepmc   +1 more source

Incidence, contributing factors, and predictors of diagnostic errors in medical inpatients: A retrospective cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx   +9 more
wiley   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar   +11 more
wiley   +1 more source

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