Results 121 to 130 of about 130,987 (296)

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Prevention of Bacterial Infection in Biliary and Pancreatic Endoscopy—A Review

open access: yesDiagnostics
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is a key therapeutic procedure in diseases of the pancreas or bile ducts. The understanding and effective management of the risks associated with the procedure, especially in the context ...
Michał Kowalski, Adam Przybyłkowski
doaj   +1 more source

Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Zubida M. Al‐Majdoub   +5 more
wiley   +1 more source

Extended Prophylactic Antibiotics for Mastectomy with Immediate Breast Reconstruction: A Meta-analysis [PDF]

open access: yes, 2020
Background: The risk of surgical site infection (SSI) for breast surgery in patients without additional risk factors is low, below 5%. Evidence shows the risk of SSI is significantly elevated in patients undergoing immediate breast reconstruction (IBR ...
Chong, Weelic, Hai, Yang, Lazar, Melissa
core   +1 more source

Control of Postharvest Brown Rot (Monilinia laxa) Disease Through Copper Sulfate and Antagonistic Bacterial Combinations

open access: yesFuture Postharvest and Food, EarlyView.
Control of brown rot (Monilinia laxa) in nectarines using eco‐friendly alternatives. Bacillus amyloliquefaciens (B10W10) and Pseudomonas sp. (B11W11), alone or with copper sulfate, significantly reduced fungal growth in vitro and disease severity in vivo.
Kenza Bouzoubaa   +4 more
wiley   +1 more source

Perioperative Piperacillin/Tazobactam Reduces Early Onset SSI in Preirradiated Patients Undergoing Microvascular Head and Neck Reconstruction

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Preirradiated patients undergoing microvascular head and neck reconstruction for tumor recurrence or osteoradionecrosis (ORN) face surgical site infection (SSI) rates exceeding 30%. The impact of perioperative extended‐spectrum antibiotic coverage remains unclear. This study hypothesizes that calculated prophylaxis with piperacillin/
Johannes G. Schuderer   +11 more
wiley   +1 more source

Is expectant management of late preterm prelabor rupture of membranes an option in patients with Group B streptococcus colonization?

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate whether expectant management of late preterm prelabor rupture of membranes (PPROM) in patients colonized with Group B streptococcus (GBS) is associated with an increased risk of adverse maternal and neonatal outcomes. Study Design This cohort study analyzed data from singleton pregnancies complicated by late PPROM between
Elior Eliasi   +6 more
wiley   +1 more source

Intrapartum oral azithromycin for maternal infection prophylaxis and the risk of postpartum hemorrhage: A secondary analysis of the A‐PLUS trial

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective A single oral dose of azithromycin (AZM) given during labor to women planning a vaginal delivery reduced maternal infections including sepsis, with a stronger effect in sub‐Saharan Africa than South Asia. Since maternal infection contributes to labor dysfunction and postpartum hemorrhage (PPH), we evaluated the effect of AZM on the ...
Larissa Sidze   +37 more
wiley   +1 more source

Maternal risk factors for postpartum readmission following vacuum‐assisted vaginal delivery: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify risk factors associated with postpartum readmission following vacuum‐assisted vaginal delivery. Methods A retrospective cohort study at a single university‐affiliated tertiary medical center from 2012 to 2023, including all singleton pregnancies delivered at ≥37 weeks' gestation.
Itamar Gilboa   +5 more
wiley   +1 more source

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