Phage-antibiotic synergy inhibited by temperate and chronic virus competition [PDF]
As antibiotic resistance grows more frequent for common bacterial infections, alternative treatment strategies such as phage therapy have become more widely studied in the medical field. While many studies have explored the efficacy of antibiotics, phage therapy, or synergistic combinations of phages and antibiotics, the impact of virus competition on ...
arxiv
Interventional studies for preventing surgical site infections in sub-Saharan Africa - A systematic review. [PDF]
BACKGROUND: There is a great need for safe surgical services in sub-Saharan Africa, but a major difficulty of performing surgery in this region is the high risk of post-operative surgical site infection (SSI).
Adjoussou+37 more
core +1 more source
The effect of local antibiotic prophylaxis when treating open limb fractures
Objectives As well as debridement and irrigation, soft-tissue coverage, and osseous stabilization, systemic antibiotic prophylaxis is considered the benchmark in the management of open fractures and considerably reduces the risk of subsequent fracture ...
M. Morgenstern+6 more
semanticscholar +1 more source
Antibiotic prophylaxis for leptospirosis
Leptospira infection is a global zoonosis with significant health impact for agricultural workers and those persons whose work or recreation takes them into endemic areas.This systematic review assessed the current literature for evidence for or against use of antibiotic prophylaxis against Leptospira infection (leptospirosis).The authors searched The ...
Brett-Major, David, Lipnick, Robert J.
openaire +5 more sources
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat+22 more
wiley +1 more source
Management of Antibiotic Prophylaxis in Mastectomy and Mammoplasty Procedures
Antibiotic prophylaxis is used to prevent infections related to surgery from the administration of antimicrobials before, during and after the procedure.
Yahanna da Costa Anacleto Estrela+2 more
doaj +1 more source
Perioperative antibiotic prophylaxis in an Australian burns unit
**Background** Perioperative antibiotic prophylaxis is perceived to reduce intraoperative bacteraemia and prevent surgical site infections, however, the evidence for its use in burns surgery is limited.
Patrick Lu+3 more
doaj +1 more source
Predicting the dynamics of bacterial growth inhibition by ribosome-targeting antibiotics [PDF]
Understanding how antibiotics inhibit bacteria can help to reduce antibiotic use and hence avoid antimicrobial resistance - yet few theoretical models exist for bacterial growth inhibition by a clinically relevant antibiotic treatment regimen. In particular, in the clinic, antibiotic treatment is time dependent.
arxiv +1 more source
Three innovations of next-generation antibiotics: evolvability, specificity, and non-immunogenicity [PDF]
Antimicrobial resistance is a silent pandemic that is being exacerbated by the uncontrolled use of antibiotics. Since the discovery of penicillin, we have been largely dependent on microbe-derived small molecules to treat bacterial infections. However, the golden era of antibiotics is coming to an end as the emergence and spread of antimicrobial ...
arxiv
The spread of multi drug resistant infections is leading to an increase in the empirical antibiotic treatment failure in cirrhosis: a prospective survey [PDF]
Background The spread of multi-resistant infections represents a continuously growing problem in cirrhosis,particularly in patients in contact with the healthcare environment.
Ceccarelli, Giancarlo+10 more
core +2 more sources