Results 151 to 160 of about 4,390,699 (400)

An antiplasmid system drives antibiotic resistance gene integration in carbapenemase-producing Escherichia coli lineages

Nature Communications
Plasmids carrying antibiotic resistance genes (ARG) are the main mechanism of resistance dissemination in Enterobacterales. However, the fitness-resistance trade-off may result in their elimination.
Pengdbamba Dieudonné Zongo, Nicolas Cabanel, Guilhem Royer, Florence Depardieu, Alain Hartmann, Thierry Naas, Philippe Glaser, Isabelle Rosinski-Chupin   +7 more
doaj   +1 more source

Genomic comparison of diverse Salmonella serovars isolated from swine. [PDF]

, 2019
Food animals act as a reservoir for many foodborne pathogens. Salmonella enterica is one of the leading pathogens that cause food borne illness in a broad host range including animals and humans.
Barrett, John B, Frye, Jonathan G, Gupta, Sushim K, Hiott, Lari M, Humayoun, Shaheen B, Jackson, Charlene R, McClelland, Michael, McMillan, Elizabeth A, Sharma, Poonam, Woodley, Tiffanie   +9 more
core   +2 more sources

Exploring patients’ profiles associated with the resolution of acute calcium pyrophosphate arthritis treatedwith colchicine and prednisone: post hoc analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Exposure of ciprofloxacin-resistant Escherichia coli broiler isolates to subinhibitory concentrations of a quaternary ammonium compound does not increase antibiotic resistance gene transfer [PDF]

, 2019
Resistance to antibiotics threatens to become a worldwide health problem. An important attributing phenomenon in this context is that pathogens can acquire antibiotic resistance genes through conjugative transfer of plasmids.
De Reu, K., Dewulf, Jeroen, Maertens, H., Meyer, Evelyne, Van Coillie, E., Van Weyenberg, S.   +5 more
core   +1 more source

Antibiotics and Antibiotic Resistance

Biomedical Journal of Scientific & Technical Research, 2017
According to the World Health Organization (WHO)’s "First Global Report on Antibiotic Resistance“, and the U.S. Centers for Disease Control & Prevention (CDC&P), the spread of "superbugs“ - bacteria that have changed in ways that render antibiotics ineffective against them - is a serious and growing threat around the world...
openaire   +2 more sources

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Targeting Antibiotic Resistance

Angewandte Chemie International Edition, 2016
AbstractFinding strategies against the development of antibiotic resistance is a major global challenge for the life sciences community and for public health. The past decades have seen a dramatic worldwide increase in human‐pathogenic bacteria that are resistant to one or multiple antibiotics.
Mathieu F. Chellat, Luka Raguž, Rainer Riedl   +2 more
openaire   +4 more sources

Illuminating New Frontiers: Exploring the Photosensitizing Potential of Passiflora Species in Combating Methicillin‐Resistant Staphylococcus aureus (MRSA) and Their Infection in Senescent Mice

Advanced Biology, EarlyView.
This study investigates the photosensitizing potential of Passiflora cincinnata in Antimicrobial Photodynamic Therapy (aPDT) against skin infection caused by Methicillin‐resistant Staphylococcus aureus (MRSA) in a senescent murine model. The P. cincinnata exhibits antimicrobial activity, with reduced bacterial load, lower leukocyte infiltration, and ...
Caroline Vieira Gonçalves, Maria Poliana Leite Galantini, Igor Pereira Ribeiro Muniz, Paulo Henrique Bispo Lima, Israel Souza Ribeiro, Maria Eduarda Santos de Oliveira, Caio Oliveira Lopes de Magalhães, Maria Elisa Santos Flores, Samara Lopes de Oliveira, Catarina Silva Guimarães, Paulinne Moreira Lima, Luísa Carregosa Santos, Daiana Silva Lopes, Juliano Geraldo Amaral, Robson Amaro Augusto da Silva   +14 more
wiley   +1 more source

Bacterial viruses enable their host to acquire antibiotic resistance genes from neighbouring cells [PDF]

, 2016
Prophages are quiescent viruses located in the chromosomes of bacteria. In the human pathogen, Staphylococcus aureus, prophages are omnipresent and are believed to be responsible for the spread of some antibiotic resistance genes.
Catalan-Moreno, Arancha, Cohn, Marianne T., Haaber, Jakob, Ingmer, Hanne, Leisner, Jørgen J., Nielsen, Jesper B., Penadés, José R., Westh, Henrik   +7 more
core   +3 more sources

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source