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In this thesis we report on several aspects of antibiotic stewardship. The increased consumption and the misuse of antibiotics have led to bacterial resistance, and therapeutic options for treating bacterial infections are being limited more and more. A post-antibiotic era lies in wait if action is not taken, as few new antibiotics have been developed ...
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Core Elements of Outpatient Antibiotic Stewardship [PDF]
The Core Elements of Outpatient Antibiotic Stewardship provides a framework for antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic treatment.
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Antibiotic consumption rates were quite high in number, although the bacterial coinfection rates were low in coronavirus disease 2019 pneumonia. Generally, empirical antibiotic treatment is not recommended for uncomplicated coronavirus disease 2019 mild ...
Halis Akalın +3 more
core +1 more source
Background Effective antibiotic prescribing is a core competency for physicians and pharmacists in combating antimicrobial resistance. Despite this, many healthcare professionals report limited confidence in applying antibiotic stewardship principles in ...
Till Koch +6 more
doaj +1 more source
Background The emerging threat of antibiotic resistance is growing exponentially and antibiotic stewardship programs are cornerstone to fight against this global threat.
Muhammad Atif +6 more
doaj +1 more source
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair +3 more
wiley +1 more source
Objectives At least 30% of outpatient antibiotic prescriptions are unnecessary. Outpatient antibiotic stewardship is needed to improve prescribing and address the threat of antibiotic resistance.
Jeffrey A Linder +6 more
doaj +1 more source
Background: Dentists prescribe ~25.7 million antibiotic prescriptions annually. Private practice dentists (PPDs) represent 80% of US dentists who need to implement dental antimicrobial stewardship.
Debra Goff +3 more
doaj +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Background This study evaluated the impact of the national antimicrobial stewardship program (NASP) on the consumption of antimicrobial agents. Methods A quasi-experimental study was conducted on hospitalized patients at a referral hospital in Tehran ...
Mohammadreza Salehi +9 more
doaj +1 more source

