Results 61 to 70 of about 439,880 (277)

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc   +2 more
wiley   +1 more source

Improving antibiotic prescribing for children in the resource-poor setting. [PDF]

open access: yes, 2015
Antibiotics are a critically important part of paediatric medical care in low- and middle-income countries (LMICs), where infectious diseases are the leading cause of child mortality. The World Health Organization estimates that >50% of all medicines are
Le Doare, Kirsty   +7 more
core   +1 more source

Challenges for interpreting results of antimicrobial susceptibility testing for treating infections of foals with Rhodococcus equi

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Rhodococcus equi is a facultative intracellular pathogen and a major cause of pneumonia in foals worldwide. The standard treatment for affected foals is a combination of a macrolide with rifampicin. The widespread use of this combination has led to the emergence of multidrug‐resistant (MDR) strains of R. equi.
Marlane Geribone Seeger   +7 more
wiley   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

open access: yesFood Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi   +6 more
wiley   +1 more source

Interpretable Machine Learning Model for Fungal Infection Prediction: A Real‐World Study

open access: yesHealth Care Science, EarlyView.
Our study successfully developed and validated a machine learning model based on large‐scale electronic health record data to predict the risk of fungal infections in hospitalized patients. Through a Streamlit‐powered web platform, the model was seamlessly embedded into clinical workflows, completing the full pipeline from model construction to real ...
Jinru Yang   +5 more
wiley   +1 more source

Modeling inpatient and outpatient antibiotic stewardship interventions to reduce the burden of Clostridioides difficile infection in a regional healthcare network.

open access: yesPLoS ONE, 2020
Antibiotic exposure can lead to unintended outcomes, including drug-drug interactions, adverse drug events, and healthcare-associated infections like Clostridioides difficile infection (CDI). Improving antibiotic use is critical to reduce an individual's
Sarah Rhea   +13 more
doaj   +1 more source

Resistance in Gram Negative Organisms: A Need for Antibiotic Stewardship

open access: yes, 2018
Antibiotic resistance is increasing in Gram Negative organisms. It is important to know the antibiogram of the hospital to start empirical therapy. It can serve as a reference to clinician looking for information on antibiotic resistance. A retrospective
Areena Hoda Siddiqui, Poonam Verma
core   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Minimum antibiotic stewardship measures [PDF]

open access: yes, 2001
An ESCMID study group on antibiotic policies (ESGAP) was formed in 1998. Several subgroups have been formed to develop key strategy in various aspects of antibiotic stewardship.
Gould, I.M.
core   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

open access: yesiMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim   +9 more
wiley   +1 more source

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