Results 211 to 220 of about 126,613 (289)

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Comparative performances of the Qvella FAST system and conventional methods for rapid identification and antibiotic susceptibility testing on monomicrobial positive blood cultures. [PDF]

J Clin Microbiol
Penven M, Louazon M, Freret C, Sauron A, Pilard M, Creignou E, Gardan O, Haumont M, Zouari A, Lorre S, Cattoir V.   +10 more
europepmc   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Microbroth dilution method for antibiotic susceptibility testing of fastidious and anaerobic bacteria of the urinary microbiome. [PDF]

Microbiol Spectr
Geaman W, Choi BI, Kaindl J, Gonzalez C, Wolfe AJ.   +4 more
europepmc   +1 more source

Inter‐Verified Binary Classification Models: Unveiling Key Polymer Features Against Staphylococcus aureus

Carbon Innovation, EarlyView.
ABSTRACT Antimicrobial peptides (AMPs) are promising alternatives to antibiotics but require precise and costly sequence control for efficacy. Synthetic polymers composed of acrylate and acrylamide offer a simpler and more time‐efficient antibacterial strategy compared to AMPs.
Jooyoung Roh, Cyrille Boyer, Priyank Kumar   +2 more
wiley   +1 more source

Multipad agarose plate: a rapid and high-throughput approach for antibiotic susceptibility testing. [PDF]

J R Soc Interface
Kals M, Mancini L, Kotar J, Donald A, Cicuta P.   +4 more
europepmc   +1 more source

The Visual Predictive Check and Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
The visual predictive check (VPC) is a standard tool for assessing pharmacometric model suitability, producing visualizations that compare observed data with simulated data such that both model structure and model variability terms can be assessed. However, real‐world data commonly reflect clinical decision‐making that adapts therapy in response to ...
Jasmine H. Hughes, Martin Bergstrand, Ron J. Keizer   +2 more
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source

Comparing Prescribing Behaviors and Clinician Experiences Between Multiplex PCR/Pooled Antibiotic Susceptibility Testing and Standard Urine Culture in Complicated UTI Cases. [PDF]

J Clin Med
Haley E, Luke N, Korman H, Rao GS, Baunoch D, Chen X, Havrilla J, Mathur M.   +7 more
europepmc   +1 more source