Results 171 to 180 of about 188,321 (291)

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Editorial: Bacterial population heterogeneity, stress response and antibiotic tolerance. [PDF]

Front Cell Infect Microbiol
Subramanian A, Kurthkoti K, Mattioni Marchetti V, Vijay S.   +3 more
europepmc   +1 more source

Lipid and polymer nanoparticles for drug delivery to bacterial biofilms [PDF]

, 2014
Braeckmans, Kevin, Coenye, Tom, De Smedt, Stefaan, Demeester, Jo, Forier, Katrien, Raemdonck, Koen   +5 more
core   +2 more sources

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Planktonic Aggregation Enhances Antibiotic Tolerance in Non-MDR Acinetobacter baumannii. [PDF]

Microorganisms
Liu J, Li Y, Liu J, Tao Z, Lu F, Tian F, Han JH, He X.   +7 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Beyond the matrix: rethinking antibiotic tolerance in CF biofilms using 3D models. [PDF]

NPJ Biofilms Microbiomes
Osondu-Chuka GO, Schandl S, Scheberl A, Guillaume O, Ovsianikov A, Reimhult E.   +5 more
europepmc   +1 more source

Antibiotics promote the sampling of luminal antigens and bacteria via colonic goblet cell associated antigen passages [PDF]

, 2017
Gustafsson, Jenny K., Kassel, Rachel, Knoop, Kathryn A., Kulkarni, Devesha H., McDonald, Keely G., Newberry, Rodney D.   +5 more
core   +2 more sources

Mechanisms of antibiotic resistance and tolerance in

Microbes and Infection, 2000
Emmanuelle Charpentier, Elaine Tuomanen
openaire   +1 more source