Results 181 to 190 of about 15,407,593 (258)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Practices and perceptions of antibiotic use in canine breeding: a survey among breeders and veterinarians. [PDF]

Front Vet Sci
Spanoghe L, Quaaden A, Lannoo J, Banchi P, Domain G, Posastiuc FP, Opsomer G, Van Soom A.   +7 more
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Electronic Clinical Quality Measures of Antibiotic Use in Hospitalized Adults With Uncomplicated Community-Acquired Pneumonia. [PDF]

Clin Infect Dis
White AT, Bidwell Goetz M, Jones M, Neuhauser MM, Ciarkowski C, Ratz D, Gupta A, Petty LA, Gandhi TN, Zhang M, Kent B, Wu C, Horowitz JK, Flanders SA, Srinivasan A, Vaughn VM.   +15 more
europepmc   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Public perceptions on antibiotic use and resistance: a social media-based multicountry survey during WAAW 2022. [PDF]

IJID Reg
Rizvi M, Mufarji AA, Shizawi NA, Jabri ZA, Haque OI, Haider M, Sami H, Malehi AA, Mohammad R, Masters K, Khan F, Mamari AA, Bahlani SA, Mohamed O, Stepanskyi D, Khan M, Shaukat A, Gautam A, M Luthfee N, Malhotra S, Agarwal J, Gur R, Siddiqui AH, Devi S, Thakuria B, Princess I, Gupta A, Sultan A, Jitendranath A, G S B, Kalita JB, Jain M, Singh NP, Mohapatra S, Farooq S, Jankhwala MS, Devi VRY, Sen M, Al-Hattali H, Al-Ghussaini HS, Ghafari MSHA, Jardani AA.   +41 more
europepmc   +1 more source

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

Using a decision support tool to reduce inappropriate antibiotic use after a delayed prescription. [PDF]

Appl Psychol Health Well Being
Sievert EDC, Gross R, Korn L, Betsch C, Böhm R.   +4 more
europepmc   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Antibiotic Use in the Emergency Department: A Retrospective Study in Indonesia. [PDF]

Antibiotics (Basel)
Kusuma IY, Benkő R, Papfalvi EP, Dewi NMAR, Nurkholis F, Nacsa R, Csupor D, Matuz M.   +7 more
europepmc   +1 more source