Results 141 to 150 of about 868,436 (327)
Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu+4 more
wiley +1 more source
Reliable uncertainty estimate for antibiotic resistance classification with Stochastic Gradient Langevin Dynamics [PDF]
Antibiotic resistance monitoring is of paramount importance in the face of this on-going global epidemic. Deep learning models trained with traditional optimization algorithms (e.g. Adam, SGD) provide poor posterior estimates when tested against out-of-distribution (OoD) antibiotic resistant/non-resistant genes.
arxiv
Induction of sister chromatid exchanges by streptonigrin, an antibiotic and antineoplastic agent
The frequencies of chromosomal aberrations and sister chromatid exchanges, SCE, were analyzed in lateral root-tip cells of Vicia faba treated with the antibiotics streptonigrin or bleomycin. Whereas both agents were very potent inducers of chromosomal aberrations in all phases of the cell cycle, only streptonigrin was able to increase the frequency of ...
openaire +2 more sources
Enaminone‐Based Push–Pull Chromophores: Synthesis, Optical Properties, and Computational Insights
Enaminones, known for their pharmacophoric properties, were combined with alkyne units to create complex chromophore structures through click‐type [2 + 2] cycloaddition‐retroelectrocyclization reactions. The ICT characteristics of the synthesized compounds were analyzed using both experimental and computational approaches.
Mehmet Mart+2 more
wiley +1 more source
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu+5 more
wiley +1 more source
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou+3 more
wiley +1 more source
When to wake up? The optimal waking-up strategies for starvation-induced persistence [PDF]
Prolonged lag time can be induced by starvation contributing to the antibiotic tolerance of bacteria. We analyze the optimal lag time to survive and grow the iterative and stochastic application of antibiotics. A simple model shows that the optimal lag time exhibits a discontinuous transition when the severeness of the antibiotic is increased.
arxiv
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo+2 more
wiley +1 more source
Weiqiang Fei,1 Jun Shen,2 Hui Cai3 1College of Nursing, Hangzhou Vocational & Technical College, Hangzhou, Zhejiang Province, People’s Republic of China; 2Nursing Department, Sir Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine,
Fei W, Shen J, Cai H
doaj