Results 141 to 150 of about 868,436 (327)

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu   +4 more
wiley   +1 more source

Reliable uncertainty estimate for antibiotic resistance classification with Stochastic Gradient Langevin Dynamics [PDF]

open access: yesarXiv, 2018
Antibiotic resistance monitoring is of paramount importance in the face of this on-going global epidemic. Deep learning models trained with traditional optimization algorithms (e.g. Adam, SGD) provide poor posterior estimates when tested against out-of-distribution (OoD) antibiotic resistant/non-resistant genes.
arxiv  

Induction of sister chromatid exchanges by streptonigrin, an antibiotic and antineoplastic agent

open access: yesHereditas, 2009
The frequencies of chromosomal aberrations and sister chromatid exchanges, SCE, were analyzed in lateral root-tip cells of Vicia faba treated with the antibiotics streptonigrin or bleomycin. Whereas both agents were very potent inducers of chromosomal aberrations in all phases of the cell cycle, only streptonigrin was able to increase the frequency of ...
openaire   +2 more sources

Enaminone‐Based Push–Pull Chromophores: Synthesis, Optical Properties, and Computational Insights

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Enaminones, known for their pharmacophoric properties, were combined with alkyne units to create complex chromophore structures through click‐type [2 + 2] cycloaddition‐retroelectrocyclization reactions. The ICT characteristics of the synthesized compounds were analyzed using both experimental and computational approaches.
Mehmet Mart   +2 more
wiley   +1 more source

Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu   +5 more
wiley   +1 more source

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou   +3 more
wiley   +1 more source

When to wake up? The optimal waking-up strategies for starvation-induced persistence [PDF]

open access: yesarXiv, 2019
Prolonged lag time can be induced by starvation contributing to the antibiotic tolerance of bacteria. We analyze the optimal lag time to survive and grow the iterative and stochastic application of antibiotics. A simple model shows that the optimal lag time exhibits a discontinuous transition when the severeness of the antibiotic is increased.
arxiv  

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo   +2 more
wiley   +1 more source

Causes of Drug-Induced Severe Cutaneous Adverse Reaction Epidermal Necrolysis (EN): An Analysis Using FDA Adverse Event Reporting System (FAERS) Database

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Weiqiang Fei,1 Jun Shen,2 Hui Cai3 1College of Nursing, Hangzhou Vocational & Technical College, Hangzhou, Zhejiang Province, People’s Republic of China; 2Nursing Department, Sir Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine,
Fei W, Shen J, Cai H
doaj  

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