Results 171 to 180 of about 30,633 (313)

Electrochemically Driven Domino Nucleophilic Addition/Diels–Alder Reaction: From 2‐Aminophenol Derivatives to Bridged Tricyclic Systems

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This electrochemical methodology allows the preparation of bridged tricyclic scaffolds through a rapid increase in the molecular complexity of simple and readily accessible starting materials. Alcohols proved to be the most efficient nucleophiles, as well as 6‐chloropurine. Plausibly, the process involves an anodic oxidative dearomatization to generate
Emanuele Cartamina   +4 more
wiley   +1 more source

An international scoping review of epidemiologic studies on severe cutaneous adverse reactions. [PDF]

open access: yesWorld Allergy Organ J
Lee J   +7 more
europepmc   +1 more source

Hofmann Degradation of Asparagine and Glutamine as an Efficient Approach for the Synthesis of Derivatized Lysine Homologs

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A practical and scalable route to C1 and C2 lysine homologs has been developed using Hofmann degradation of N‐protected L‐asparagine and L‐glutamine as the key step. These short‐tether scaffolds enable efficient synthesis of diverse Fmoc‐protected noncanonical amino acids (ncAAs) bearing donor, acceptor, redox‐active, and fluorescent residues.
Adelaide R. Mashweu   +7 more
wiley   +1 more source

White Hairy Tongue Post-Linezolid Therapy. [PDF]

open access: yesIndian Dermatol Online J
Somasundaram A, Karthik L, Kumar S.
europepmc   +1 more source

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević   +4 more
wiley   +1 more source

Rates of Drug-Induced Uveitis: A Review by Medication Class. [PDF]

open access: yesClin Ophthalmol
Jasti R   +4 more
europepmc   +1 more source

Fermentation‐Induced Modulation of Polyphenolic Contents and Medicinal Activities in Annona squamosa Seeds

open access: yesFood Chemistry International, EarlyView.
The study compared the medicinal activities of polyphenols from fermented and unfermented seeds of Annona squamosa. The polyphenols were extracted and subjected to standard analysis. The major phenolic components of the fermented polyphenols and the unfermented polyphenols were found to be 4‐hydroxybenzoic and 4‐hydroxyphenylacetic acid, respectively ...
Shola Hezekiah Awojide   +10 more
wiley   +1 more source

Effect of Fruit Maturation Stage on the Chemical Composition and Antioxidant and Cytotoxic Activities of Piper nigrum Essential Oil

open access: yesFlavour and Fragrance Journal, EarlyView.
The essential oils of Piper nigrum show marked chemical and biological variation across fruit maturation stages. Ripe fruits yield oils with the strongest antioxidant and cytotoxic activities, demonstrating that maturation directly modulates volatile composition and enhances the bioactive potential of this aromatic species.
Marcio Marcelo da Siva Pessoa   +6 more
wiley   +1 more source

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