Results 131 to 140 of about 12,384 (179)

Antineutrophil cytoplasmic antibodies in children

European Journal of Pediatrics, 1998
To define the diagnostic meaning of antineutrophil cytoplasmic antibodies (ANCA) positivity in children, we analysed 1485 consecutive sera sent for routine immunological investigation to our department from January to August 1996. Using this large screening, we identified the most typical clinical disorders associated with ANCA in childhood.
A, Sedivá, I, Kolárová, J, Bartůnková   +2 more
openaire   +2 more sources

“Hide and seek” with antineutrophil cytoplasmic antibodies

American Journal of Otolaryngology, 2010
“Hide and seek” with antineutrophil cytoplasmic antibodies Matteo Alicandri-Ciufelli, MD, Gabriele Molteni, MD⁎, Maria Teresa Mascia, MD, Elisabetta Genovese, MD, Livio Presutti, MD Department of Otolaryngology-Head and Neck Surgery, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy Department of Rheumatology, Azienda Ospedaliero ...
ALICANDRI CIUFELLI, Matteo, MOLTENI, Gabriele, MASCIA, Maria Teresa, GENOVESE, Elisabetta, PRESUTTI, Livio   +4 more
openaire   +2 more sources

The mystery of the antineutrophil cytoplasmic antibodies

American Journal of Kidney Diseases, 1995
A NTINEUTROPHIL cytoplasmic antibodies (ANCAs) were first reported in eight patients with segmental necrotizing glomerulonephritis and serologic evidence for acute Ross River virus infection, an arbovirus endemic in Australia that causes a febrile polyartbritis syndrome.’ Subsequently ANCAs were reported in patients with systemic vasculitis.’ Two major
openaire   +2 more sources

Testing for antineutrophil cytoplasmic antibodies

Expert Review of Molecular Diagnostics, 2001
The most common reason to request a test for antineutrophil cytoplasmic antibodies (ANCA) is to diagnose Wegener's granulomatosis and microscopic polyangiitis and to monitor inflammatory activity in these diseases. Several retrospective and prospective studies have suggested that the demonstration of ANCA lacks sensitivity and specificity, but these ...
openaire   +2 more sources

Antineutrophil cytoplasmic antibodies

American Journal of Medicine, 1992
Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease from the azurophilic granules.
Kallenberg, Cees G. M., Mulder, A. H. Leontine, Tervaert, Jan Willem Cohen   +2 more
openaire   +1 more source

Antineutrophil cytoplasmic antibodies (ANCA) and vasculitis

Clinical Rheumatology, 1990
The demonstration of autoantibodies to different myeloid lysozomal enzymes has opened a new area for the study of vasculitic syndromes. Autoantibodies producing a granular cytoplasmic staining by IIF (c-ANCA, probably directed to a putative serine protease) are closely associated with Wegener's granulomatosis.
openaire   +3 more sources

Antineutrophil cytoplasmic antibodies and their relevance to the dermatologist

British Journal of Dermatology, 2006
The term vasculitis embraces a heterogeneous group of conditions which may occur as primary phenomena or secondary to disorders such as rheumatoid arthritis or systemic lupus erythematosus. Classification of vasculitis is often difficult in the absence of identifiable aetiological factors or specific serological markers.
N P, Burrows, C M, Lockwood
openaire   +2 more sources

Antineutrophil Cytoplasmic Antibodies Testing and Interpretation

Clinics in Laboratory Medicine, 2019
The discovery of antineutrophil cytoplasmic antibodies (ANCA) helped establish ANCA-associated vasculitis as a separate and well-defined clinical entity. Its progressive incorporation into the clinical diagnosis algorithms has made ANCA testing a cornerstone immunoassay embedded in the management of ANCA-associated vasculitis.
Hugues, Allard-Chamard, Patrick, Liang
openaire   +2 more sources

Clinical value of antineutrophil cytoplasmic antibodies

Current Rheumatology Reports, 2000
This article presents a brief review of the clinical value of antineutrophil cytoplasmic antibodies (ANCA) in the diagnosis and management of patients with various forms of vasculitis. ANCA assay methodology and testing recommendations are reviewed. The patterns of reactivity of ANCA observed by indirect immunofluorescence, the antigens recognized by ...
V, Rus, B S, Handwerger
openaire   +2 more sources

Antineutrophil Cytoplasmic Antibodies in Diffuse Panbronchiolitis

Respiration, 1999
<i>Background:</i> There are some reports of the coexistence of chronic suppurative lung diseases such as cystic fibrosis and systemic vasculitis. Diffuse panbronchiolitis has the same characteristics as chronic recurrent sinopulmonary infection and respiratory bronchiolitis.
Y, Sugiyama, S, Kitamura
openaire   +2 more sources