Results 1 to 10 of about 68,092 (120)

Myeloperoxidase: a new target for the treatment of stroke?

Neural Regeneration Research, 2022
Myeloperoxidase is an important inflammatory factor in the myeloid system, primarily expressed in neutrophils and microglia. Myeloperoxidase and its active products participate in the occurrence and development of hemorrhagic and ischemic stroke ...
Yun-Chang Wang, Yu-Bao Lu, Xiao-Lan Huang, Yong-Feng Lao, Lu Zhang, Jun Yang, Mei Shi, Hai-Long Ma, Ya-Wen Pan, Yi-Nian Zhang   +9 more
doaj   +1 more source

What is the role of the neutrophil extracellular traps in the cardiovascular disease burden associated with hemodialysis bioincompatibility?

Frontiers in Medicine, 2023
Despite significant progress in dialysis modalities, intermittent renal replacement therapy remains an “unphysiological” treatment that imperfectly corrects uremic disorders and may lead to low-grade chronic inflammation, neutrophil activation, and ...
Jean-Paul Cristol, Jean-Paul Cristol, Alain R. Thierry, Anne-Sophie Bargnoux, Marion Morena-Carrere, Bernard Canaud, Bernard Canaud   +6 more
doaj   +1 more source

Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1). [PDF]

PLoS ONE, 2017
Myeloperoxidase is the major peroxidase enzyme in neutrophil granules and implicated in contributing to inflammatory lung damage in cystic fibrosis. Free myeloperoxidase is present in cystic fibrosis lung fluid and generates hypochlorous acid.
Pamela S Hair, Laura A Sass, Neel K Krishna, Kenji M Cunnion   +3 more
doaj   +1 more source

The relation of serum myeloperoxidase to disease progression and mortality in patients with chronic obstructive pulmonary disease (COPD). [PDF]

PLoS ONE, 2013
Myeloperoxidase is a strong oxidant stored in primary granules of neutrophils with potent antibacterial and proatherogenic properties. Myeloperoxidase has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD).
Hye Yun Park, S F Paul Man, Donald Tashkin, Robert A Wise, John E Connett, Nicholas A Anthonisen, Don D Sin   +6 more
doaj   +1 more source

Upper respiratory tract manifestations in patients with ANCA-associated vasculitides and their association with the presence and type of ANCA

Научно-практическая ревматология, 2021
Aim of the work – to compare the frequency of upper respiratory tract (URT) involvement in patients with ANCAassociated vasculitides (AAV), to reveal its main clinical and radiological patterns and to estimate their association with the serological ...
I. G. Smirnova, N. M. Bulanov, P. I. Novikov, I. A. Osipova, S. V. Moiseev   +4 more
doaj   +1 more source

Myeloperoxidase and Advanced Oxidation Protein Products in the Cerebrospinal Fluid in Women and Men with Parkinson’s Disease

Antioxidants, 2022
Background: Myeloperoxidase (MPO) and advanced oxidation protein products, or AOPP (a type of MPO-derived chlorinated adducts), have been implicated in Parkinson´s disease (PD). Human MPO also show sex-based differences in PD.
Emilio Fernández-Espejo, Fernando Rodríguez de Fonseca, Ana Luisa Gavito, Antonio Córdoba-Fernández, José Chacón, Ángel Martín de Pablos   +5 more
doaj   +1 more source

Comparing hs-CRP and MPO Biomarkers of Subclinical Atherosclerosis in Metabolic Syndrome Patients

Journal of Pure and Applied Microbiology, 2023
Cardiovascular disorders have been linked to myeloperoxidase, an enzyme generated from leukocytes. MPO creates an antibacterial system and has been many correlations between MPO, hs-CRP and cardiovascular disease.
Abishkauf Jenish Beautlin, Ashok Govindaraj, Durga Devi, Gurubharath Ilangovan, Divya Lakshmi   +4 more
doaj   +1 more source

The oxidative status in patients with chronic kidney disease [PDF]

The Ukrainian Biochemical Journal, 2020
An excess of free radicals accompanies the development of renal pathologies and causes numerous concomitant complications and syndromes. The most common of these are cardiometabolic syndromes in patients with chronic kidney disease.
V. S. Vasylchenko, L. V. Korol, O. B. Kuchmenko, N. M. Stepanova   +3 more
doaj   +1 more source

Automatic Identification of Myeloperoxidase Natural Inhibitors in Plant Extracts

Molecules, 2022
The aim of this study is the development of an automated method for myeloperoxidase activity evaluation and its application in testing the inhibitory action of different plant extracts on the activity of the enzyme.
Fátima A. R. Mota, Sarah A. P. Pereira, André R. T. S. Araújo, Beatriz Gullón, Marieta L. C. Passos, Maria Lúcia M. F. S. Saraiva   +5 more
doaj   +1 more source

M2 Monocyte Polarization in Dialyzed Patients Is Associated with Increased Levels of M-CSF and Myeloperoxidase-Associated Oxidative Stress: Preliminary Results

Biomedicines, 2021
Cardiovascular diseases represent a major issue in terms of morbidity and mortality for dialysis patients. This morbidity is due to the accelerated atherosclerosis observed in these patients.
Valérie Pireaux, Cédric Delporte, Alexandre Rousseau, Jean-Marc Desmet, Pierre Van Antwerpen, Martine Raes, Karim Zouaoui Boudjeltia   +6 more
doaj   +1 more source