Results 21 to 30 of about 92,132 (290)

Ageing enhances cellular immunity to myeloperoxidase and experimental anti-myeloperoxidase glomerulonephritis [PDF]

, 2021
OBJECTIVES: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disease characterised by small blood vessel inflammation, commonly affecting the kidneys and respiratory tract.
Alikhan, Maliha A, Jaw, Juli, Heeringa, Peter; id_orcid, Holdsworth, Stephen R, Kitching, A Richard, Robson, Kate J, Brouwer, Elisabeth, Shochet, Lani R, Ooi, Joshua D, Maliha A Alikhan, Stephen R Holdsworth, Peter Heeringa, Kate J Robson, Joshua D Ooi, A Richard Kitching, Elisabeth Brouwer, Lani R Shochet, Juli Jaw   +17 more
core   +1 more source

Evaluation of expression of genes associated with post-thrombotic syndrome [PDF]

Jornal Vascular Brasileiro
Prediction of the development of post-thrombotic syndrome (PTS) among patients with deep venous thrombosis (DVT) is currently based on clinical characteristics alone; no reliable biomarkers are available.
Ricardo André Viana Barros, Erika Mota Herenio, Mariana Rocha Maximiano, Julia Hellena Mendes Ribeiro, Octávio Luiz Franco, Robert Edward Pogue   +5 more
doaj   +1 more source

Myeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective

, 2022
Antibodies to neutrophil and monocyte myeloperoxidase and proteinase 3 are a feature of anti-neutrophil cytoplasmic antibody vasculitis, a disease with significant morbidity for which new treatments are needed.
Adrian Freeman, Attila Mócsai, Fernanda Florez-Barros, Kull, Bengt, Mócsai, Attila, Michael G. Robson, Bengt Kull, Freeman, Adrian, Florez-Barros, Fernanda, Bearder, Siobhan, Siobhan Bearder, Robson, Michael G   +11 more
core   +1 more source

Biodegradability of Carbon Nano-Onions by Human Myeloperoxidase and the Photo-Fenton Reaction [PDF]

, 2023
The biodegradability of graphene family materials (GFMs) in the environment and organisms is little understood to estimate their fate and possible byproducts. Herein, for the first time, we explored the biodegradability of multilayer fullerenes or carbon
Dr. Rajendra, Kurapati, Swetha, K, Prathiksha, K, Michał, Bartkowski, Akash , Garhwal, Silvia, Giordani, Adalberto, Camisasca, Ananya , Aravind   +7 more
core   +2 more sources

Presence of Myeloperoxidase in Lamellar Tissue of Horses Induced by an Euglycemic Hyperinsulinemic Clamp

Frontiers in Veterinary Science, 2022
Laminitis is a pathology of the equine digit leading to a failure of the dermo-epidermal interface. Neutrophil activation is recognized as a major factor in SIRS-associated laminitis.
Nazare Storms, Carlos Medina Torres, Thierry Franck, Albert Sole Guitart, Geoffroy de la Rebière, Didier Serteyn, Didier Serteyn   +6 more
doaj   +1 more source

Clinical profile of acute myeloid leukemia in North India and utility of nontransplant measures in its management

Indian Journal of Medical and Paediatric Oncology, 2019
Introduction: Acute myeloid leukemia (AML) is a clonal accumulation of myeloid precursors in body tissues, which ultimately leads to bone marrow failure. This is an 8-year prospective, observational study in which 254 patients were enrolled.
Nadeem Shoket, Javvid Muzamil, Tasneef Banoo Zargar, Burhan Wani, Vishal Toka, Javid Rasool Bhat, Gull Mohammad Bhat, Aejaz Aziz Shiekh   +7 more
doaj   +1 more source

Effects of Jian Pi Qing Chang Hua Shi decoction on mucosal injuries in a 2,4,6-trinitrobenzene sulphonic acid-induced inflammatory bowel disease rat model

Pharmaceutical Biology, 2021
Context Jian Pi Qing Chang Hua Shi decoction (JPQCHSD) has been considered as an effective remedy for the treatment of inflammatory bowel disease (IBD) in Chinese traditional medicine.
Huicun Zhang, Na Ta, Hong Shen, Hongbing Wang   +3 more
doaj   +1 more source

Salivary profile of matrix metalloproteinase-8, tissue inhibitors of matrix metalloproteinase-1, myeloperoxidase, and nitrous oxide in smokers versus nonsmokers with chronic periodontitis

Journal of International Clinical Dental Research Organization, 2021
Background: Smoking is the second strongest modifiable risk factor for periodontal disease. Tissue destruction might result from matrix metalloproteinase (MMP)/tissue inhibitors of MMP (TIMP) imbalance in the diseased tissues.
Deepti Gattani, Jigyasa Sahu, Nupur Kar, Ritika Gattani   +3 more
doaj   +1 more source

Protein Oxidation Biomarkers and Myeloperoxidase Activation in Cerebrospinal Fluid in Childhood Bacterial Meningitis

Antioxidants, 2019
The immunological response in bacterial meningitis (BM) causes the formation of reactive oxygen and nitrogen species (ROS, RNS) and activates myeloperoxidase (MPO), an inflammatory enzyme. Thus, structural oxidative and nitrosative damage to proteins and
Emilie Rugemalira, Irmeli Roine, Julia Kuligowski, Ángel Sánchez-Illana, José David Piñeiro-Ramos, Sture Andersson, Heikki Peltola, Manuel Leite Cruzeiro, Tuula Pelkonen, Máximo Vento   +9 more
doaj   +1 more source

Neutrophil-Derived Myeloperoxidase Facilitates Both the Induction and Elicitation Phases of Contact Hypersensitivity

Frontiers in Immunology, 2021
BackgroundAllergic contact dermatitis (ACD) is a common skin disorder affecting an estimated 15-20% of the general population. The mouse model of ACD is contact hypersensitivity (CHS), which consists of two phases: induction and elicitation.
Anna Strzepa, Anna Strzepa, Cody J. Gurski, Landon J. Dittel, Marian Szczepanik, Kirkwood A. Pritchard, Bonnie N. Dittel, Bonnie N. Dittel   +7 more
doaj   +1 more source