Diagnostic Value of Myeloperoxidase Index in Bacterial Infections [PDF]
, 2021 Infectious diseases remain a serious problem in Indonesia. Myeloperoxidase (MPO) is a substance released by neutrophils, which activates the synthesis of hypochlorous acid (HOCL) from hydrogen peroxide (H2O2) and chloride ion (Cl-).
Paulus Budiono Notopuro +2 more
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Ageing enhances cellular immunity to myeloperoxidase and experimental anti-myeloperoxidase glomerulonephritis [PDF]
, 2022 OBJECTIVES: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disease characterised by small blood vessel inflammation, commonly affecting the kidneys and respiratory tract.
Heeringa, Peter +9 more
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Frontiers in Immunology, 2020 Francisella tularensis(Ft) is a highly virulent, intracellular Gram-negative bacterial pathogen. Acute Ft infection by aerosol route causes pneumonic tularemia, characterized by nodular hemorrhagic lesions, neutrophil-predominant influx, necrotic debris,
Sivasami Pulavendran +7 more
doaj +1 more source
Effect of antibiotics on polymorphonuclear leukocyte functions and myeloperoxidase activity, glutathione and malondialdehyde levels in allergic asthma [PDF]
, 2015 We investigated the effect of ciprofloxacin, rifampicine and doxycycline on myeloperoxidase (MPO) activity, glutathione (GSH) and malondialdehyde (MDA) levels in allergic asthma patients and healthy volunteers.
SOYOĞUL GÜRER, ÜMRAN +2 more
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Evaluation of expression of genes associated with post-thrombotic syndrome [PDF]
Jornal Vascular BrasileiroPrediction of the development of post-thrombotic syndrome (PTS) among patients with deep venous thrombosis (DVT) is currently based on clinical characteristics alone; no reliable biomarkers are available.
Ricardo André Viana Barros +5 more
doaj +1 more source
Chlorination and oxidation of heparin and hyaluronan by hypochlorous acid and hypochlorite anions: effect of sulfate groups on reaction pathways and kinetics. [PDF]
, 2013 Hypochlorous acid (HOCl), produced in inflammatory conditions by the enzyme myeloperoxidase, and its anion hypochlorite (OCl(-)) exist in vivo at almost equal concentrations.
Parsons, BJ +4 more
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Reactions of Superoxide with Myeloperoxidase† [PDF]
, 2016 When neutrophils ingest bacteria, they discharge superoxide and myeloperoxidase into phagosomes. Both are essential for killing of the phagocytosed micro-organisms.
Anthony J. Kettle (2403607) +3 more
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Myeloperoxidase inhibition ameliorates plaque psoriasis in mice [PDF]
, 2021 Plaque psoriasis is a common inflammatory condition of the skin characterized by red, flaking lesions. Current therapies for plaque psoriasis target many facets of the autoimmune response, but there is an incomplete understanding of how oxidative damage ...
Neu, Savannah D. +11 more
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Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling [PDF]
, 2017 Rationale: Ventricular arrhythmias remain the leading cause of death in patients suffering myocardial ischemia. Myeloperoxidase, a heme enzyme released by polymorphonuclear neutrophils, accumulates within ischemic myocardium and has been linked to ...
Florian G. Deuschl +55 more
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Myeloperoxidase in human intracranial aneurysms: preliminary evidence [PDF]
, 2015 BACKGROUND AND PURPOSE: Noninvasive imaging identifying a predictive biomarker of the bleeding risk of unruptured intracranial aneurysms (UIAs) is needed. We investigated a potential biomarker of UIA instability, myeloperoxidase, in human aneurysm tissue.
Vedantham, Srinivasan +6 more
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