Results 161 to 170 of about 674,963 (207)

Antineutrophil Cytoplasmic Antibodies in Chronic Liver Diseases: Prevalence, Titre, Specificity and IgG Subclass

Journal of Hepatology, 1996
BACKGROUND/AIMS: Antineutrophil cytoplasmic antibodies are reported in patients with chronic liver disease, but controversy exists about their prevalence and specificity.
Roger Chapman, Kenneth Fleming, D Bansi
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Antineutrophil cytoplasmic antibodies

The Lancet, 2006
Much like other autoantibodies (eg, anti-double stranded DNA in systemic lupus erythematosus or antiglomerular basement membrane antibodies in Goodpasture's syndrome), antineutrophil cytoplasmic antibodies (ANCA) have provided doctors with a useful serological test to assist in diagnosis of small-vessel vasculitides, including Wegener's granulomatosis,
Bosch, Xavier, Guilabert, Antonio, Font, Josep   +2 more
openaire   +4 more sources

Testing for Antineutrophil Cytoplasmic Antibodies

Expert Review of Molecular Diagnostics, 2001
The most common reason to request a test for antineutrophil cytoplasmic antibodies (ANCA) is to diagnose Wegener's granulomatosis and microscopic polyangiitis and to monitor inflammatory activity in these diseases. Several retrospective and prospective studies have suggested that the demonstration of ANCA lacks sensitivity and specificity, but these ...
Judy Savige
exaly   +3 more sources

Vasculitis and Antineutrophil Cytoplasmic Autoantibodies Associated With Propylthiouracil Therapy

Lancet, The, 1993
Vasculitis is a rare complication of propylthiouracil therapy. Antineutrophil cytoplasmic antibodies (ANCA) have been described in association with several vasculitic disorders. We report detection of ANCA against human neutrophil elastase, proteinase 3,
K M Dolman, A J Donker, A E von dem Borne   +2 more
exaly   +2 more sources

Antineutrophil cytoplasmic antibodies in children

European Journal of Pediatrics, 1998
To define the diagnostic meaning of antineutrophil cytoplasmic antibodies (ANCA) positivity in children, we analysed 1485 consecutive sera sent for routine immunological investigation to our department from January to August 1996. Using this large screening, we identified the most typical clinical disorders associated with ANCA in childhood.
A, Sedivá, I, Kolárová, J, Bartůnková   +2 more
openaire   +2 more sources

Antineutrophil Cytoplasmic Antibodies.

Lancet, The, 1989
R A Thompson, R A Thompson
exaly   +2 more sources

The mystery of the antineutrophil cytoplasmic antibodies

American Journal of Kidney Diseases, 1995
A NTINEUTROPHIL cytoplasmic antibodies (ANCAs) were first reported in eight patients with segmental necrotizing glomerulonephritis and serologic evidence for acute Ross River virus infection, an arbovirus endemic in Australia that causes a febrile polyartbritis syndrome.’ Subsequently ANCAs were reported in patients with systemic vasculitis.’ Two major
openaire   +2 more sources

Antineutrophil cytoplasmic antibodies

American Journal of Medicine, 1992
Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease from the azurophilic granules.
Kallenberg, Cees G. M., Mulder, A. H. Leontine, Tervaert, Jan Willem Cohen   +2 more
openaire   +1 more source

Clinical value of antineutrophil cytoplasmic antibodies

Current Rheumatology Reports, 2000
This article presents a brief review of the clinical value of antineutrophil cytoplasmic antibodies (ANCA) in the diagnosis and management of patients with various forms of vasculitis. ANCA assay methodology and testing recommendations are reviewed. The patterns of reactivity of ANCA observed by indirect immunofluorescence, the antigens recognized by ...
V, Rus, B S, Handwerger
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Antineutrophil cytoplasmic antibodies (ANCA) and vasculitis

Clinical Rheumatology, 1990
The demonstration of autoantibodies to different myeloid lysozomal enzymes has opened a new area for the study of vasculitic syndromes. Autoantibodies producing a granular cytoplasmic staining by IIF (c-ANCA, probably directed to a putative serine protease) are closely associated with Wegener's granulomatosis.
openaire   +3 more sources