Anticorpos contra o citoplasma de neutrófilos Antineutrophil cytoplasmic antibodies [PDF]
A descoberta do marcador sorológico denominado anticorpo anticitoplasma de neutrófilos revolucionou o diagnóstico e o seguimento das vasculites pulmonares, especialmente da granulomatose de Wegener. Seu padrão pode ser citoplasmático e perinuclear.
Ari Stiel Radu, Mauricio Levi
doaj +2 more sources
Antineutrophil cytoplasmic antibodies-associated glomerulonephritis: From bench to bedside
Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) is a group of autoimmune disorders that predominantly affects small vessels. The onset of the disease is closely associated with ANCA.
Yong-Xi Chen, Xiao-Nong Chen
doaj +2 more sources
Myeloperoxidase-antineutrophil Cytoplasmic Antibodies with Cytoplasmic Fluorescence Pattern
ABSTRACTWe report here two rare cases of myeloperoxidase–antineutrophil cytoplasmic antibody (MPO-ANCA)-positive Wegener’s granulomatosis (limited variant) which deceptively produced a cytoplasmic (C-ANCA) pattern on indirect immunofluorescence.
Chhabra, Seema +3 more
openaire +3 more sources
Background Antineutrophil cytoplasmic antibody-associated vasculitis is dominated by inflammatory occlusion of small vessels, causing tissue ischemia in various organs.
Maassoumeh Akhlaghi Kalahroodi +4 more
doaj +1 more source
Antineutrophil cytoplasmic antibodies: appropriate use and interpretation [PDF]
It was with much interest that we read the letter of Novikov et al 1 on testing for antineutrophil cytoplasmic antibodies (ANCAs) in patients with ANCA-associated vasculitides (AAV) and other diseases. In their letter, the authors (1) share their experience with direct testing for proteinase-3 (PR3) ANCA and myeloperoxidase (MPO) ANCA and (2) raise ...
Damoiseaux, Jan +4 more
openaire +2 more sources
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Antineutrophil cytoplasmic antibodies: reporting and diagnostic strategies [PDF]
It was with great interest that we read the correspondence of Mahler and Fritzler1 on our recent European Vasculitis Study Group (EUVAS) study describing the performance of immunoassays for antineutrophil cytoplasmic antibodies (ANCA) in patients with ANCA-associated vasculitides (AAV).2 In their letter, Mahler and Fritzler raise some interesting ...
Damoiseaux, Jan +4 more
openaire +3 more sources
Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Folwaczny, Christian +15 more
core +1 more source
Antineutrophil cytoplasmic antibodies (ANCA)
Antineutrophil cytoplasmic antibodies (ANCA) are a sensitive and specific marker for ANCA-associated systemic vasculitis. Using indirect immunofluorescence on ethanol-fixed neutrophils, two major fluoroscopic patterns can be recognised: a diffuse cytoplasmic staining (C-ANCA), and a perinuclear/nuclear staining (P-ANCA).
Radice, A, SINICO, RENATO ALBERTO
openaire +2 more sources
Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
Török, H.-P. +9 more
core +1 more source

