Results 51 to 60 of about 17,550 (209)

An uncommon presentation of eosinophilic granulomatosis with polyangiitis: a case report [PDF]

, 2014
INTRODUCTION: Eosinophilic granulomatosis with polyangiitis is a rare and potentially fatal disease if not readily diagnosed. Cerebral involvement is extremely rare and clinical presentation as hemorrhagic stroke is even rarer.
Andolina, G, Banco, MA, Bonura, A, BUSCEMI, Silvio, COSTANZA GAGLIO, Edy, TAORMINA, Giuseppe   +5 more
core   +2 more sources

Antineutrophil cytoplasmic antibodies-associated glomerulonephritis: From bench to bedside

Chronic Diseases and Translational Medicine, 2018
Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) is a group of autoimmune disorders that predominantly affects small vessels. The onset of the disease is closely associated with ANCA.
Yong-Xi Chen, Xiao-Nong Chen
doaj   +1 more source

ANCA-associated vasculitis [PDF]

, 2017
The vasculitides are a heterogeneous group of conditions typified by their ability to cause vessel inflammation with or without necrosis. They present with a wide variety of signs and symptoms and, if left untreated, carry a significant burden of ...
Watts, Richard, Yates, Max
core   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

The Effect of Intranasal Niclosamide on Nasal Symptoms in Patients with Anti‐Neutrophil Cytoplasmic Antibody‐Associated Vasculitis

Arthritis &Rheumatology, Accepted Article.
Objective Ear, nose and throat (ENT) manifestations are common in ANCA‐associated vasculitis (AAV). There is unmet need for drugs to target these manifestations. Granuloma formation is characteristic of proteinase 3 (PR3)‐AAV. In a zebrafish model, niclosamide inhibits PR3‐induced granuloma formation.
Benjamin Lim, Wendi Qian, Francis Dowling, Alan Salama, Rona Smith   +4 more
wiley   +1 more source

Pediatric Inflammatory Bowel Disease with Cytoplasmic Staining of Antineutrophil Cytoplasmic Antibodies

Clinical and Developmental Immunology, 2013
Background. It is unusual for the antineutrophil cytoplasmic antibody with cytoplasmic pattern (cANCA) to present in patients with inflammatory bowel disease (IBD) without vasculitis.
Omar I. Saadah, Jamil A. Al-Mughales
doaj   +1 more source

Nasal manifestations in granulomatosis with polyangiitis: a case report and review of the literature [PDF]

, 2018
Granulomatosis with polyangiitis (GPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides of medium and small arteries, characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract with coexist ...
D'AGUANNO, VITTORIO, DE VINCENTIIS, Marco, FALASCA, VINCENZO, GRECO, Antonio, RALLI, MASSIMO, TURCHETTA, Rosaria   +5 more
core   +1 more source

Prediction of Relapse and Glucocorticoid Dependence in Eosinophilic Granulomatosis with Polyangiitis: Findings from a Large European Cohort

Arthritis &Rheumatology, Accepted Article.
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterized by eosinophilia, asthma, and ear, nose, throat (ENT) involvement. Although glucocorticoids (GCs) are effective in controlling symptoms, relapses and GC dependence are common.
Matthias Papo, Pauline Martinot, Renato A. Sinico, Vítor Silvestre‐Teixeira, Nils Venhoff, Maria‐Letizia Urban, Michele Iudici, Juliane Mahrhold, Francesco Locatelli, Giulia Cassone, Franco Schiavon, Benjamin Seeliger, Thomas Neumann, Claudia Feder, Matthieu Groh, Chiara Marvisi, Maxime Samson, Thomas Barba, David Jayne, Arianna Troilo, Jens Thiel, Bernhard Hellmich, Sara Monti, Carlomaurizio Montecucco, Carlo Salvarani, Jean‐Emmanuel Kahn, Bernard Bonnotte, Cécile‐Audrey Durel, Xavier Puéchal, Luc Mouthon, Loïc Guillevin, Giacomo Emmi, Augusto Vaglio, Raphaël Porcher, Benjamin Terrier, The French Vasculitis Study Group and the EGPA European Study Group   +35 more
wiley   +1 more source

Cytoplasmic-anti-neutrophil cytoplasmic antibodies targeting myeloperoxidase in Wegener′s granulomatosis: A rare phenomenon

Indian Journal of Pathology and Microbiology, 2014
Wegener′s granulomatosis (WG) patients can rarely have antineutrophil cytoplasmic antibodies (ANCAs) directed against myeloperoxidase (MPO), producing a cytoplasmic pattern on indirect immunofluorescence (IIF).
Bhavana M Venkatesh, Sangeeta Joshi, Ranjeeta Adhikary   +2 more
doaj   +1 more source

Granulomatosis with Polyangiitis Misdiagnosed as IgA Vasculitis in a Child

Case Reports in Pediatrics, 2023
Background. Granulomatosis with polyangiitis (GPA) with early manifestations simulating IgA vasculitis is a very rare childhood systemic disease. Case Presentation.
Sheida Amini, Mohsen Jari
doaj   +1 more source