Results 81 to 90 of about 17,550 (209)

Serological markers for prediction of response to anti-tumor necrosis factor treatment in Crohn's disease [PDF]

, 2002
peer reviewedOBJECTIVES: The use of monoclonal anti-tumor necrosis factor (TNF) antibodies (infliximab, Remicade) is a new therapeutic approach for severe refractory luminal or fistulizing, Crohn's disease (CD).
Belaiche, J, Belgian Group of Infliximab Expanded Access Program in Crohn's Disease, Bossuyt, X, De Vos, M, Esters, N, Fiasse, René, Joossens, S, Louis, E, Noman, M, Pelckmans, P, Pescatore, P, Poulain, D, Reynaert, H, Rutgeerts, P, Van Gossum, A, Vermeire, S   +15 more
core   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Antineutrophil cytoplasmic antibodies in Chinese patients with tuberculosis

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Based on reports, infection with Mycobacterium tuberculosis is believed to induce the development of antibodies that are considered to be biological indicators for the diagnosis of some other diseases.
Gao Huan, Gao Yang, Qu Xiao-yu, Xu Jiancheng, Song Yan-qing   +4 more
doaj   +1 more source

Vasculitides associated with IgG antineutrophil cytoplasmic autoantibodies in childhood [PDF]

, 2018
Immunoglobulin (Ig)G antineutrophil cytoplasmic autoantibodies are causally associated with necrotizing vasculitides that are characterized immunopathologically by little or no deposition of immunoreactants, such as Wegener granulomatosis, microscopic ...
Bettinelli, Alberto, Bianchetti, Mario, Keller, Franco, Simonetti, Giacomo, Vanoni, Federica   +4 more
core  

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity. [PDF]

, 2012
Antineutrophil cytoplasmic antibodies (ANCAs) target proteins normally retained within neutrophils, indicating that cell death is involved in the autoimmunity process. Still, ANCA pathogenesis remains obscure.
Abdgawad, Alcorta, Barbara Cappetti, Bennett, Bianchi, Brinkmann, Carla Guarnotta, Cassatella, Caterina Vitali, Chin, Claudia Chiodoni, Claudio Tripodo, Clayton, Colombo, Cristiana Guiducci, Di Carlo, Dittmar, Donnelly, Drenkard, Falk, Fuchs, Gaipl, Galeazzi, Garcia-Romo, Gilligan, Griffith, Guiducci, Jarius, Kantari, Kessenbrock, Lande, Manolova, Mariella Parenza, Mario P. Colombo, Martinelli, Metzler, Munafo, Nagata, Nathan, Patrizia Casalini, Patry, Potter, Pradhan, Remijsen, Sabina Sangaletti, Sangaletti, Santiago-Raber, Silvia Piconese, Specks, Spronk, Steinman, Tripodo, van der Geld, van Timmeren, Villanueva, Wernick, Witko-Sarsat, Ziegler-Heitbrock   +57 more
core   +1 more source

Overlapping forms of granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis: Insights from a European multicenter study

Journal of Internal Medicine, Volume 299, Issue 3, Page 349-364, March 2026.
Abstract Background Granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) are distinct forms of antineutrophil cytoplasm antibody (ANCA)‐associated vasculitis (AAV). Increasing evidence suggests overlapping features, particularly in proteinase 3 (PR3)‐ANCA‐positive EGPA and GPA with eosinophilia.
Federica Pallotti, Camille Mettler, Matthias Papo, Michele Iudici, Roberto Padoan, Boris Sorin, Francesca Regola, Franco Franceschini, Sergey Moiseev, Pavel Novikov, Mario Andrea Piga, Gianluca Moroncini, Silke R. Brix, Abdul Hadi Kafagi, Samuel Deshayes, Achille Aouba, Julien Campagne, Paolo Delvino, Jan Willem Cohen Tervaert, Luisa Brussino, Martin Michaud, Nils Venhoff, Federico Alberici, Claudia Iannone, Sophie Rosenstingl, Marin Moutel, Jean‐Marc Galempoix, Vincent Cottin, Clara Jaccard, Diane Riehl, Paul Legendre, Anne Claire Billet, Paola Parronchi, Luca Quartuccio, Vitor Teixeira, Allyson Egan, David Jayne, Enrico Tombetti, Marco Caminati, Christian Pagnoux, Alexis Regent, Marc Ruivard, Loïc Guillevin, Xavier Puéchal, Benjamin Terrier, the French Vasculitis Study Group (FVSG)   +45 more
wiley   +1 more source

P-ANCA vasculitis in a patient with Alpha-1-Antitrypsin deficiency : a possible mechanism [PDF]

, 2009
Antineutrophil cytoplasmic antibody (ANCA) testing plays a critical role in the diagnosis and classification of vasculitis. These antibodies are strongly associated with Wegener's granulomatosis, microscopic polyangiitis and Churg-Strauss syndrome ...
Tuffaha, Ahmad
core  

Clinic manifestations in granulomatosis with polyangiitis [PDF]

, 2016
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco, De Virgilio, Armando, Fusconi, Massimo, Gallo, Andrea, Greco, Antonio, Macri, Gian Franco, Marinelli, Caterina, Zambetti, Giampietro   +7 more
core   +1 more source

An Atypical Presentation of Tubulointerstitial Nephritis With Uveitis (TINU) in an Older Patient Requiring Emergency Dialysis: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) is an immune‐mediated systemic disorder most commonly described in adolescents and young adults, and its recognition in older patients remains challenging. We report the case of a 58‐year‐old woman who presented with systemic symptoms and rapidly progressive acute kidney injury.
Yuli Yang, Yangna Shi, Jian Li, Jing Meng, Wenyu Gong   +4 more
wiley   +1 more source

Frequency of Antineutrophil Cytoplasmic Antibodies (ANCA) in Some Autoimmune Diseases

Iraqi Journal of Pharmaceutical Sciences, 2017
Anti-Neutrophil Cytoplasmic Antibodies (ANCA) are a heterogeneous group of autoantibodies with a broad spectrum of clinically associated diseases. The diagnostic value is established for Proteinase 3 (PR3)-ANCA as well as Myeloperoxidase (MPO)-ANCA.
Falah S. Manhal, Husam M. Abbas
doaj   +3 more sources