Results 121 to 130 of about 54,568 (249)

Progressive Soft Tissue Swelling in a Pediatric Patient Leading to the Diagnosis of Fibrodysplasia Ossificans Progressiva: A Case Report

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by progressive heterotopic ossification (HO) and congenital malformation of the great toes. This case describes a 5‐year‐old Caucasian girl who initially presented with painless neck and back swelling as well as severe limitation of movement in the neck and ...
Orhan Yilmaz, Loretta Fiorillo
wiley   +1 more source

Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19. [PDF]

open access: yes, 2020
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus pandemic (COVID-19).
Fitzgerald, Robert L   +5 more
core  

Juvenile Dermatomyositis Triggered by Influenza B: A Case Report on Viral‐Induced Autoimmunity

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT A previously healthy 13‐year‐old boy developed juvenile dermatomyositis (JDM) shortly after a confirmed influenza B infection, presenting with progressive proximal muscle weakness and classic cutaneous findings. Laboratory tests revealed elevated muscle enzymes and myositis‐specific autoantibodies, supporting the diagnosis.
Santiago Dans‐Caballero   +4 more
wiley   +1 more source

Blau Syndrome (Juvenile Systemic Granulomatosis): State‐Of‐The‐Art Review

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Blau syndrome (BlauS) is a rare pediatric autoinflammatory disorder due to NOD2 gain‐of‐function pathogenic variants characterized by a triad of granulomatous dermatitis, arthritis, and uveitis, which can progress to systemic complications if untreated.
Ou Jia (Emilie) Wang   +3 more
wiley   +1 more source

Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group [PDF]

open access: yes, 2012
Introduction: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known.
Abdel Atty Mohamed, Walid A.   +24 more
core  

Viruses and the Conntective Tissue Diseases [PDF]

open access: yes, 1974
A number of observations in the last few years have attracted attention to the possibility of viral infection in systemic lupus erythematosus (SLE). One of these is the occurrence of interwoven tubular structures, usually in the endothelial cells of the ...
Ziff, Morris
core   +1 more source

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

open access: yesThe Journal of Pathology, Volume 266, Issue 4-5, Page 369-389, August 2025.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk   +5 more
wiley   +1 more source

Modulation of interferon-[alpha] secretion by activated platelets in systemic lupus erythematosus. [PDF]

open access: yes, 2008
Type I interferons play a key role in systemic lupus erythematosus (SLE) pathogenesis as an "IFN signature" is found in the majority of patients with active SLE.
Bernard Weill   +8 more
core   +1 more source

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri   +10 more
wiley   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 15, Page 3411-3427, August 2025.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou   +4 more
wiley   +1 more source

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