Can Antinuclear Antibodies (ANA) be Monoclonal?
Background. Nuclear staining by immunofluorescence in a kidney biopsy is often seen in patients with positive antinuclear antibodies (ANA) in the serum. These ANA are usually polyclonal, but herein we report 9 cases with an unusual finding of monoclonal ...
Laura Biederman +7 more
doaj +1 more source
Immunological Impact of Ovarian Cystectomy in Cases of Laparscopic Procedure and Conventional Laparotomy [PDF]
Background: Conventional and laparoscopic surgery can impact a patient's immune status. Laparotomy causes more tissue trauma, while laparoscopy uses more cauterization, making both procedures potentially dangerous for the immune system.
Magdy Olama +2 more
doaj +1 more source
Antimelanocyte antibodies: A possible role in patients with vitiligo
Background: Vitiligo is an acquired depigmenting skin disorder with multifactorial pathogenesis including genetic, autoimmune, and neuronal factors. Both humoral- and cell-mediated immunities are supposed to have a role in the pathogenesis of vitiligo ...
Maha A El-Gayyar +4 more
doaj +1 more source
Antinuclear antibodies in primary pulmonary hypertension [PDF]
The association of positive antinuclear antibodies with the clinical and hemodynamic features of 43 patients with primary pulmonary hypertension and 16 patients with secondary pulmonary hypertension was investigated.
Rich, Stuart +5 more
core +1 more source
Assessment of Serum Prolactin Level in Patients Women with Rheumatoid Arthritis
The prolactin hormone played role in the many autoimmune disorders. To determine the importance of high levels of prolactin in triggering rheumatoid arthritis, thirty patient's women with hyperprolactinemia aged (20-45) years old have been investigated ...
Baghdad Science Journal
doaj +1 more source
Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Török, H.-P. +5 more
core +1 more source
Nuclear Antigens and Auto/Alloantibody Responses: Friend or Foe in Transplant Immunology
In addition to cellular immune responses, humoral immune responses, mediated by natural antibodies, autoantibodies, and alloantibodies, have increasingly been recognized as causes of organ transplant rejection.
Toshiaki Nakano +2 more
doaj +1 more source
Development of a Machine Learning Algorithm for Differential Diagnosis Between Primary Immune Thrombocytopenia and Connective Tissue Disease-Related Thrombocytopenia in Pediatric Patients. [PDF]
Primary immune thrombocytopenia (ITP) and connective tissue disease‐related thrombocytopenia (CTD‐TP) share overlapping initial presentations in children, often leading to delayed diagnosis and suboptimal management. While existing literature focuses on therapeutic strategies, this study is the first to develop a machine learning (ML)‐based diagnostic ...
Kang F, Yan M, Yue Y, Wang X, Liu Y.
europepmc +2 more sources
Antinuclear antibodies in rosacea patients [PDF]
IntroductionRosacea is a common inflammatory disorder, characterized by a spectrum of facial manifestations. The clinical similarity to other dermatoses, like lupus erythematosus, might lead to misdiagnosis, particularly in patients with elevated ...
Woźniacka, Anna +3 more
core +1 more source
ANTINUCLEAR ANTIBODIES IN PATIENTS WITH UNEXPLAINED RECURRENT ABORTIONS [PDF]
Objective:This study aims to determine the prevalence of antinuclear antibodies in pregnant women with bad obstetric history (BOH) against healthy multigravid women in and around Tirunelveli districtMethods: This is a case-control study comprising 60 ...
S, Manivelan +3 more
core +3 more sources

