Results 41 to 50 of about 529,151 (288)

CVID-associated TACI mutations affect autoreactive B cell selection and activation [PDF]

, 2013
Common variable immune deficiency (CVID) is an assorted group of primary diseases that clinically manifest with antibody deficiency, infection susceptibility, and autoimmunity.
Tuure Kinnunen, Gentile, M, Cantaert, T, Tineke Cantaert, Menard, L, Laurence Menard, Morbach, H, Saadoun, D, Virdee, M, Neil Romberg, Kinnunen, T, Maurizio Gentile, Rachid, R, Martinez-Pomar, N, Geha, R, Henner Morbach, Matamoros, N, Cunningham-Rundles, C, Nicolas Chamberlain, Nuria Matamoros, Andrea Cerutti, Yen Shing Ng, Bodo Grimbacher, Natalia Martinez-Pomar, Meffre, E, Eric Meffre, David Saadoun, Manmeet Virdee, Rima Rachid, Cerutti, A, Raif Geha, Romberg, N, Brimbacher, B, Chamberlain, N, Charlotte Cunningham-Rundles, Ng, YS   +35 more
core   +1 more source

Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy

Przegląd Dermatologiczny, 2018
Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal, Marta Sar-Pomian, Joanna Czuwara, Lidia Rudnicka   +3 more
doaj   +1 more source

Catastrophic Antiphospholipid Syndrome after Orthotopic Liver Transplant

Case Reports in Transplantation, 2022
Background. Catastrophic antiphospholipid syndrome (CAPS) is an autoimmune thrombogenic disorder of small and large vessels caused by autoantibodies against phospholipids and phospholipid-binding proteins.
R. Okeke, J. Lok, R. Wells, M. Wycoff, A. Engelhardt, J. Bettag, C. O’Leary, T. Hallcox, M. Nazzal   +8 more
doaj   +1 more source

Autoantibody profiles and their association with blood eosinophils in asthma and COPD

Allergology International, 2017
Background: Autoimmune involvement in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD) has been proposed, and autoantibodies are a hallmark of autoimmunity.
Koji Tamai, Harukazu Yoshimatsu, Toshiharu Saito, Hirofumi Matsuoka, Nobuhiko Okada, Yasuko Koma, Akiko Otsuka, Nao Oda, Sayaka Inoue, Sachie Kume, Yujiro Suzuki   +10 more
doaj   +1 more source

Clinical diagnoses associated with a positive antinuclear antibody test in patients with and without autoimmune disease

BMC Rheumatology, 2023
Background Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals will develop an autoimmune disease, and ...
Jacy T. Zanussi, Juan Zhao, Wei-Qi Wei, Gul Karakoc, Cecilia P. Chung, QiPing Feng, Nancy J. Olsen, C. Michael Stein, Vivian K. Kawai   +8 more
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Comparative Evaluation of Indirect Immunofluorescence and Immunoblot Techniques for Antinuclear Antibody Detection in Pakistani Patients [PDF]

Indian Journal of Medical Biochemistry
Aims and background: This study aims to evaluate indirect immunofluorescence assay (IFA) and immunoblot (IBM) methods for antinuclear antibody (ANA) detection in Pakistani patients and to investigate the correlation between autoimmune diseases and ...
Nazneen Perveen, Faiza Naz, Beena Hasan, Syed ZA Naqvi, Sobia Rafiq   +4 more
doaj   +1 more source

Female–Male Distribution in Autoantibody Detected by Immunofluorescence

Experimed, 2020
Objective: This study determines the positivity rates and gender distribution of antinuclear and liver-specific autoantibodies that are considered important in the diagnosis and follow-up of autoimmune diseases.
Nuray Gürel Polat, Nurhas Safran, Gaye Erten Yurdagül   +2 more
doaj   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source