Results 41 to 50 of about 1,505,633 (297)

The importance of detecting anti-DFS70 in routine clinical practice : comparison of different care settings [PDF]

, 2018
Background: Screening for antinuclear antibodies by indirect immunofluorescence (ANA-IIF) is essential in the diagnostic workup of ANA-associated autoimmune rheumatic diseases (AARDs).
Berth, Mario, Bonroy, Carolien, Devreese, Katrien, Hoffman, Ilse, Piette, Yves, Schouwers, Sofie, Stubbe, Muriel, Van Hoovels, Lieve   +7 more
core   +2 more sources

Clinical diagnoses associated with a positive antinuclear antibody test in patients with and without autoimmune disease

BMC Rheumatology, 2023
Background Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals will develop an autoimmune disease, and ...
Jacy T. Zanussi, Juan Zhao, Wei-Qi Wei, Gul Karakoc, Cecilia P. Chung, QiPing Feng, Nancy J. Olsen, C. Michael Stein, Vivian K. Kawai   +8 more
doaj   +1 more source

Immune myopathies with perimysial pathology: Clinical and laboratory features [PDF]

, 2018
ObjectiveImmune myopathies with perimysial pathology (IMPP) have a combination of damage to perimysial connective tissue and muscle fiber necrosis, more prominent near the perimysium.
Bucelli, Robert C, Pestronk, Alan
core   +2 more sources

Epidemiological survey of antinuclear antibodies in healthy population and analysis of clinical characteristics of positive population

Journal of clinical laboratory analysis (Print), 2019
In China, the incidence of autoimmune diseases is gradually increasing. To decrease the misdiagnosis rate of autoimmune diseases, we conducted an epidemiological investigation about the presence of antinuclear antibody (ANA) in healthy populations and ...
Xiaoyan Li, Xin Liu, Jingjing Cui, Wenjie Song, Ying Liang, Yue-Chun Hu, Yaping Guo   +6 more
semanticscholar   +1 more source

Antinuclear antibodies

Autoimmunity, 2005
The presence of abnormal levels of autoantibodies to intracellular antigens is a hallmark of systemic connective tissue disease. The indirect immunofluorescence assay is the most commonly used routine test for the detection of antinuclear antibodies.
openaire   +2 more sources

Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]

, 2019
OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M, Farinha, F, Mendonça, T, Urzal, J   +3 more
core   +1 more source

Antinuclear antibodies in healthy people and non-rheumatic diseases – diagnostic and clinical implications

Rheumatology, 2018
The presence of antinuclear antibodies (ANA) is mainly associated with connective tissue diseases (CTD). In addition, their presence is found in healthy people. These antibodies are more common in women and the elderly.
B. Grygiel-Górniak, Natalia Rogacka, M. Puszczewicz   +2 more
semanticscholar   +1 more source

Autoantibody profiles and their association with blood eosinophils in asthma and COPD

Allergology International, 2017
Background: Autoimmune involvement in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD) has been proposed, and autoantibodies are a hallmark of autoimmunity.
Koji Tamai, Harukazu Yoshimatsu, Toshiharu Saito, Hirofumi Matsuoka, Nobuhiko Okada, Yasuko Koma, Akiko Otsuka, Nao Oda, Sayaka Inoue, Sachie Kume, Yujiro Suzuki   +10 more
doaj   +1 more source

International consensus on antinuclear antibody patterns: definition of the AC-29 pattern associated with antibodies to DNA topoisomerase I

Clinical Chemistry and Laboratory Medicine, 2018
The indirect immunofluorescence assay (IFA) on HEp-2 cells is the reference method for autoantibody screening. The HEp-2 IFA pattern provides useful information on the possible autoantibodies in the sample.
L. Andrade, W. Klotz, M. Herold, K. Conrad, J. Rönnelid, M. Fritzler, C. V. von Mühlen, M. Satoh, J. Damoiseaux, W. de Melo Cruvinel, E. Chan   +10 more
semanticscholar   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source