Results 51 to 60 of about 1,482,108 (303)

International consensus on antinuclear antibody patterns: definition of the AC-29 pattern associated with antibodies to DNA topoisomerase I

Clinical Chemistry and Laboratory Medicine, 2018
The indirect immunofluorescence assay (IFA) on HEp-2 cells is the reference method for autoantibody screening. The HEp-2 IFA pattern provides useful information on the possible autoantibodies in the sample.
L. Andrade, W. Klotz, M. Herold, K. Conrad, J. Rönnelid, M. Fritzler, C. V. von Mühlen, M. Satoh, J. Damoiseaux, W. de Melo Cruvinel, E. Chan   +10 more
semanticscholar   +1 more source

Antinuclear Antibodies: Marker of Diagnosis and Evolution in Autoimmune Diseases

Laboratoriums Medizin, 2018
Antinuclear antibodies (ANAs) are autoantibodies that attack self-proteins within cell nucleus structures; their presence in serum may indicate an autoimmune disease.
L. Sur, Emanuela Floca, Daniel G Sur, Marius C Colceriu, G. Samașca, G. Sur   +5 more
semanticscholar   +1 more source

Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey. [PDF]

, 2016
BackgroundFirst reported in 1955, Cronkhite-Canada syndrome (CCS), a rare syndrome characterized by ectodermal abnormalities and inflammatory changes of the gastrointestinal tract mucosa, has been associated with a poor prognosis and life-threatening ...
Hibi, Toshifumi, Hirata, Ichiro, Hokari, Ryota, Kaunitz, Jonathan D, Komoto, Shunsuke, Miura, Soichiro, Tanaka, Masanori, Tomita, Kengo, Watanabe, Chikako   +8 more
core   +1 more source

A sore red eye with systemic involvement [PDF]

, 2010
The study of happiness has long been a playground for philosophical speculation. By lack of empirical measures of happiness, it was not possible to check propositions about the matter.
Lightman, SL, Pusey, CD, Shalchi, Z, Taylor, SRJ   +3 more
core   +2 more sources

Fully automated chemiluminescence microarray immunoassay for detection of antinuclear antibodies in systemic autoimmune rheumatic diseases

Journal of Laboratory Medicine
Detection of specific antinuclear antibodies is very important in term of diagnosis, prognosis and management of patients with systemic autoimmune rheumatic diseases.
Yuan Dandan, Yang Xue, Ji Chen, Sun Guo, Xu Yang, Cao Ye, Ye Yan, Wang Tingting, Hu Zhigang   +8 more
doaj   +1 more source

Recent Approaches To Optimize Laboratory Assessment of Antinuclear Antibodies

Clinical and Vaccine Immunology, 2017
The presence of antinuclear antibodies (ANAs) is a hallmark of a number of systemic autoimmune rheumatic diseases, and testing is usually performed as part of the initial diagnostic workup when suspicion of an underlying autoimmune disorder is high.
A. Tebo
semanticscholar   +1 more source

Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell–Targeting Treatment in Patients With Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective The presence of antinuclear antibodies (ANAs) is characteristic for systemic lupus erythematosus (SLE). Antibody dynamics over time are thought to reflect the cellular source of ANAs and their therapeutic targetability. Anti–double‐stranded DNA (anti‐dsDNA) is the most prevalent and well‐studied of all ANAs, and fluctuations in anti‐dsDNA ...
Hugo J. van Dooren, Mieke van Schaik, Annemarie L. Dorjée, Eline J. Arends, Meggan Mackay, Laura Cooney, David A. Fox, David Wofsy, Dawn Smilek, Cynthia Aranow, Maria Dall'Era, Tom W. J. Huizinga, Cees van Kooten, René E. M. Toes, Betty Diamond, Y. K. Onno Teng, Jolien Suurmond   +16 more
wiley   +1 more source

High Proportions of People With Nonceliac Wheat Sensitivity Have Autoimmune Disease or Antinuclear Antibodies.

Gastroenterology, 2015
BACKGROUND & AIMS There is much interest in wheat sensitivity among people without celiac disease (CD), but little is known about any risks associated with the condition.
A. Carroccio, A. D’alcamo, F. Cavataio, M. Soresi, A. Seidita, C. Sciumé, G. Geraci, G. Iacono, P. Mansueto   +8 more
semanticscholar   +1 more source

Hand Swelling and Other Non–Raynaud Phenomenon Symptoms as the Initial Presentation of Systemic Sclerosis: Prevalence and Clinical Associations in Two US Cohorts

Arthritis &Rheumatology, EarlyView.
Objective Raynaud phenomenon (RP) is often the initial clinical manifestation of systemic sclerosis (SSc), but some patients develop other manifestations first. To help elucidate the diversity of SSc presentation in its early stages, we describe the initial clinical manifestations and antinuclear antibody (ANA) profiles of patients in two early SSc ...
Iqtidar Hanif, Shervin Assassi, Maureen D. Mayes, Zsuzsanna H. McMahan, Meng Zhang, Julio Charles, John M. VanBuren, Jessica S. Alvey, Kimia Ghaffari, Elana J. Bernstein, Flavia V. Castelino, Lorinda Chung, Luke Evnin, Tracy M. Frech, Jessica K. Gordon, Faye N. Hant, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Jerry A. Molitor, Duncan F. Moore, Carrie Richardson, Nora Sandorfi, Ami A. Shah, Ankoor Shah, Victoria K. Shanmugam, Virginia D. Steen, Elizabeth R. Volkmann, Carleigh Zahn, Brian Skaug   +32 more
wiley   +1 more source

The importance of detecting anti-DFS70 in routine clinical practice : comparison of different care settings [PDF]

, 2018
Background: Screening for antinuclear antibodies by indirect immunofluorescence (ANA-IIF) is essential in the diagnostic workup of ANA-associated autoimmune rheumatic diseases (AARDs).
Berth, Mario, Bonroy, Carolien, Devreese, Katrien, Hoffman, Ilse, Piette, Yves, Schouwers, Sofie, Stubbe, Muriel, Van Hoovels, Lieve   +7 more
core   +2 more sources