The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Antinuclear antibodies in children with Wilson’s disease
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O. V. Kurbatova+16 more
doaj +1 more source
Antinuclear antibodies in postinfectious smell loss - a pilot study [PDF]
Background: Numerous diseases are mediated by autoimmune mechanisms some of which have been shown to be associated with reduced olfactory function, e.g. systemic lupus erythematosus, Sjögren syndrome, psoriasis vulgaris.
U. Walliczek-Dworschak+3 more
doaj +1 more source
IgG, IgM, and IgA Antinuclear Antibodies in Discoid and Systemic Lupus Erythematosus Patients
IgG antinuclear antibodies (ANAs) are elevated in patients with systemic lupus erythematosus (SLE) compared with patients with discoid lupus erythematosus (DLE).
Sheridan Jost+6 more
semanticscholar +1 more source
Association Between SARS-CoV-2 Vaccination and Development of Antinuclear Antibodies Among Students
Introduction: Antinuclear antibodies (ANA) are the hallmark of many connective tissue disorders (including lupus), which comprise roughly 5% to 10% of chronic debilitating diseases causing morbidity and mortality.
Karol Laskowski+4 more
doaj +1 more source
Agreement of three commercial anti-extractable nuclear antigen tests: EUROASSAY Anti-ENA Profile, Polycheck Autoimmune Test and FID Connective Profile [PDF]
BackgroundDetection of antibodies to extractable nuclear antigens (ENAs) is needed for the diagnosis in systemic autoimmune diseases. In this study, we compared three reagents using line immunoblot assay (LIA) or multiplex bead immunoassay for detecting ...
Namhee Kim+4 more
doaj +1 more source
Evaluation of the primary biliary cholangitis-related serologic profile in a large cohort of Belgian systemic sclerosis patients [PDF]
Background: Systemic sclerosis (SSc) and primary biliary cholangitis (PBC) are autoimmune diseases that may occur concomitantly and are both strongly associated with disease-specific autoantibodies.
Bonroy, Carolien+6 more
core +1 more source
High Prevalence of Antinuclear Antibodies in Children with Thyroid Autoimmunity
Background. Antinuclear antibodies (ANA) are a hallmark of many autoimmune diseases and can be detected many years before disease onset. Autoimmune thyroid diseases (AITD) are frequently associated with other organ- and non-organ-specific autoimmune ...
M. Segni+5 more
semanticscholar +1 more source
Antinuclear Autoantibodies in Health: Autoimmunity Is Not a Synonym of Autoimmune Disease
The incidence of autoimmune diseases is increasing. Antinuclear antibody (ANA) testing is a critical tool for their diagnosis. However, ANA prevalence in healthy persons has increased over the last decades, especially among young people.
I. Pashnina+6 more
semanticscholar +1 more source
Voclosporin‐induced gingival enlargement: A case report
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca+2 more
wiley +1 more source