Results 91 to 100 of about 413,379 (310)

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Utility of serological markers in inflammatory bowel diseases: Gadget or magic?

, 2007
The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Although anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely ...
Papp, Mária, Lakatos, Péter László, Norman, G. L., Altorjay, István   +3 more
core  

Protocol for developing Pseudomonas aeruginosa type III secretion system-neutralizing monoclonal antibodies from human B cells

STAR Protocols
Summary: Monoclonal antibodies (mAbs) targeting bacterial virulence factors may represent promising therapeutics in the fight against severe bacterial infections. Here, we present an approach for developing human-derived antibodies targeting the type III
Alexandra Albus, Christoph Kreer, Florian Klein, Jan Rybniker, Alexander Simonis   +4 more
doaj   +1 more source

Epitope mapping of antibodies using bacterial surface display

, 2008
We describe a method for mapping the epitopes recognized by antibodies, based on bacterial surface expression of antigen protein fragments followed by antibody-based flow-cytometric sorting. We analyzed the binding sites of both monoclonal and polyclonal
Rockberg, Johan,, Hjelm, Barbara,, Ståhl, Stefan,, Barbara Hjelm, Mathias Uhlén, Löfblom, John,, Uhlén, Mathias,, Johan Rockberg, John Löfblom, Stefan Ståhl   +9 more
core   +1 more source

BACTERIAL QUANTIFICATION AND ANTI-BACTERIAL ANTIBODIES IN OTITIS MEDIA WITH EFFUSION IN CHILDREN

Nippon Jibiinkoka Gakkai Kaiho, 1993
Quantification of bacterial flora in middle ear effusions (MEE) and adenoids in children with otitis media with effusion (OME) was performed. IgG, IgA and IgM titers against H. influenzae, S. pneumoniae, S. mitis, S. sanguis, and S. salivarius were measured in MEE, sera and the supernatant of adenoid lymphocyte cultures.
openaire   +3 more sources

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

Cellular delivery of antibodies: effective targeted subcellular imaging and new therapeutic tool

, 2010
It is already more than a century since the pioneering work of the Nobel Laureate Ehrlich gave birth to the side chain theory1, which helped to define antibodies and their ability to target specific biological sites.
Nicholas J. Warren, Steven P. Armes, Marzia Massignani, Nisa Patikarnmonthon, Andrew L. Lewis, Giuseppe Battaglia, Irene Canton   +6 more
core  

On the Transference of Bacterial Antibodies from the Hen to the Chick [PDF]

Journal of General Microbiology, 1952
SUMMARY: Agglutinins against Salmonella pullorum and Salm. typhi (strain O 901) were induced in hens by intravenous inoculation with killed suspensions and were transferred to the yolks of their eggs. This transference of antibody continued throughout a laying season of about 280 days, and the relationship between the agglutinin titres of sera and ...
openaire   +2 more sources

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Extracellular Polysaccharides from Xanthomonas axonopodis pv. manihotis Interact with Cassava Cell Walls During Pathogenesis

Molecular Plant-Microbe Interactions, 1997
The location of lipopolysaccharides produced by Xanthomonas axonopodis pv. manihotis during pathogenesis on cassava (Manihot esculenta) was determined by fluorescence and electron microscopy immunolabeling with monoclonal antibodies.
B. Boher, M. Nicole, M. Potin, J. P. Geiger   +3 more
doaj   +1 more source