Results 151 to 160 of about 417,575 (218)

Targeting a conserved flagellin D1 epitope with 16G10 confers cross-serotype protection in murine <i>Pseudomonas aeruginosa</i> infection models. [PDF]

Hum Vaccin Immunother
Wang Y, Wang Y, Zhu Z, Wang Q, Liu X, Cai Q, Zhang Y, Li Y, Zhao H, Cheng X, Gu J, Zou Q, Jiang J.   +12 more
europepmc   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

The hidden threat: understanding anti-PF4 disorders without proximate heparin exposure. [PDF]

Front Immunol
Liu Z, Li Y, Ma L, Wang X, Cui Y.
europepmc   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

<i>Coxiella burnetii</i> inhibits host cell death by ubiquitination-induced inactivation of an apoptosis nuclease. [PDF]

mLife
Zhang Y, Jiao J, Liu S, Yuan J, Liu S, Chen TT, Ouyang S, Fu J, Luo ZQ.   +8 more
europepmc   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Intravenous anti-P. aeruginosa IgY antibodies increase bacterial concentration in porcine septic shock with bacteremia. [PDF]

Intensive Care Med Exp
Otterbeck A, Skorup P, Larsson A, Stålberg J, Baumgarten M, Lampinen M, Hjelmqvist H, Lipcsey M.   +7 more
europepmc   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Subclinical exposure to Streptococcus pyogenes drives the development of long-lived homologous immunity. [PDF]

Nat Commun
Lepletier A, Vedis D, Ozberk V, Anugraham M, Bessette D, Short C, Calcutt A, Frost HR, Azzopardi KI, Steer AC, Kolarich D, Osowicki J, Good MF, Pandey M.   +13 more
europepmc   +1 more source