Results 171 to 180 of about 23,804 (223)
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The Role of Antibody in Parasitic Helminth Infections
2014A wealth of data on the protective immune mechanisms induced following helminth infection exist, but how antibody responses protect against helminth infections is unclear and shows variation between species. Understanding antibody responses to different helminth species is important to support the future development of anti-helminth vaccines that will ...
Erin, Logan +2 more
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Antibody to Interleukin-5 Inhibits Helminth-Induced Eosinophilia in Mice
Science, 1989When rodents are infected with the nematode Nippostrongylus brasiliensis , large numbers of eosinophils appear in their blood and lungs and their serum immunoglobulin E (IgE) is increased. Injection of a monoclonal antibody to interleukin-5 completely suppressed the blood eosinophilia and the infiltration of ...
R L, Coffman +4 more
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The preparation and use of radiolabelled specific Helminth antibodies
The International Journal of Applied Radiation and Isotopes, 1983Specific antibodies from the serum of sheep infected with Haemonchus contortus were isolated by combination with a “solid phase antigen” (soluble antigen coupled to an activated crystalline cellulose). The antibodies were labelled with 125I while bound to the solid phase then eluted and their potential demonstrated: (1) to determine amounts of specific
M. Movsesijan +3 more
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Importance of Antibody Class in Helminth Infections
1989Antibodies play an important role in the rejection of many parasites. They are essential for immune recognition of antigens incorporated in the surface of large nonphagocytosable helminths. Thus by focusing host defense mechanisms against the intact parasite they may ultimately lead to parasite rejection.
N. M. Almond, R. M. E. Parkhouse
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Reagin-like Antibodies in Animals Immune to Helminth Parasites
Nature, 1964RECENT investigations here have shown that rats, monkeys and sheep infected with helminth parasites produce an antibody with many of the properties of human reagin. Naturally occurring persistent antibodies of this type have not been demonstrated previously in animals, although in rats an antibody similar in its biological properties but transitory in ...
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Veterinary Immunology and Immunopathology, 2017
Dietary phytonutrients such as cinnamaldehyde (CA) may contribute to immune function during pathogen infections, and CA has been reported to have positive effects on gut health when used as feed additive for livestock. Here, we investigated whether CA could enhance antibody production and specific immune responses during infection with an enteric ...
Williams, Andrew Richard +6 more
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Dietary phytonutrients such as cinnamaldehyde (CA) may contribute to immune function during pathogen infections, and CA has been reported to have positive effects on gut health when used as feed additive for livestock. Here, we investigated whether CA could enhance antibody production and specific immune responses during infection with an enteric ...
Williams, Andrew Richard +6 more
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In vitro parasite antigen-induced antibody responses in human helminth infections.
The Journal of Immunology, 1985Abstract Helminth parasites characteristically induce vigorous antibody responses in human infections, but the immunoregulatory mechanisms determining the level of these responses are not at all understood. To investigate these mechanisms, peripheral blood mononuclear cells were obtained from 10 patients with parasitic helminth ...
T B, Nutman, A S, Withers, E A, Ottesen
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Journal of Parasitology, 2000
Intermediate filaments (IFs) make up the cytoskeleton of most eukaryotic cells. In vertebrates, a number of IF proteins have been identified, showing distributions unique to tissue or cell type. Information on helminth IFs is limited to some nematode species.
H, Sato, H, Kamiya
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Intermediate filaments (IFs) make up the cytoskeleton of most eukaryotic cells. In vertebrates, a number of IF proteins have been identified, showing distributions unique to tissue or cell type. Information on helminth IFs is limited to some nematode species.
H, Sato, H, Kamiya
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Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis.
The Journal of Immunology, 1991Abstract Rodents infected with the nematode parasite Nippostrongylus brasiliensis (Nb) develop intestinal mastocytosis, eosinophilia, and elevated serum IgE levels. Although IL-4 and IL-5 are necessary for stimulation of IgE synthesis and eosinophilia, respectively, the cytokines that regulate gut mast cell hyperplasia have not been ...
K B, Madden +5 more
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Journal of Immunological Methods, 1994
An enzyme-linked immunosorbent assay (ELISA) using antigenic beta-galactosidase-helminth derived recombinant fusion protein (FP) obtained by the recombinant DNA technique provided a useful diagnostic tool for human helminthiasis. Helminth-infected human sera reacted strongly with FP that was immobilized with anti-beta-galactosidase monoclonal antibody ...
K, Sugane, S H, Sun
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An enzyme-linked immunosorbent assay (ELISA) using antigenic beta-galactosidase-helminth derived recombinant fusion protein (FP) obtained by the recombinant DNA technique provided a useful diagnostic tool for human helminthiasis. Helminth-infected human sera reacted strongly with FP that was immobilized with anti-beta-galactosidase monoclonal antibody ...
K, Sugane, S H, Sun
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