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Modeling the contribution of antibody attack rates to single and dual helminth infections in a natural system

Mathematical Biosciences, 2023
Within-host models of infection can provide important insights into the processes that affect parasite spread and persistence in host populations. However, modeling can be limited by the availability of empirical data, a problem commonly encountered in natural systems.
Vanalli C.   +5 more
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A theoretical framework for the immunoepidemiology of blocking antibodies to helminth infection

Parasite Immunology, 1994
SUMMARYEpidemiological evidence is widely cited in support of the hypothesis that certain antibody responses to human helminth, especially schistosome, infection exhibit blocking activity. This evidence includes positive correlations between antibody levels and the rate of re‐establishment of infection following chemotherapy, antibody levels which peak
openaire   +2 more sources

Reagin-like Antibodies in Animals Immune to Helminth Parasites

Nature, 1964
RECENT investigations here have shown that rats, monkeys and sheep infected with helminth parasites produce an antibody with many of the properties of human reagin. Naturally occurring persistent antibodies of this type have not been demonstrated previously in animals, although in rats an antibody similar in its biological properties but transitory in ...
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Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis

The Journal of Immunology, 1991
Abstract Rodents infected with the nematode parasite Nippostrongylus brasiliensis (Nb) develop intestinal mastocytosis, eosinophilia, and elevated serum IgE levels. Although IL-4 and IL-5 are necessary for stimulation of IgE synthesis and eosinophilia, respectively, the cytokines that regulate gut mast cell hyperplasia have not been ...
K B, Madden   +5 more
openaire   +2 more sources

Antigen-Antibody Reactions in Helminth Infections

1963
Publisher Summary Work on the antigen-antibody reactions in helminth infections has involved a wide range of mammalian species as hosts and has also included almost the complete range of parasitic helminths. Nevertheless, despite their large size and multifarious migrations, the helminths generally stimulate satisfactory immune responses that can be ...
openaire   +1 more source

Dietary cinnamaldehyde enhances acquisition of specific antibodies following helminth infection in pigs

Veterinary Immunology and Immunopathology, 2017
Dietary phytonutrients such as cinnamaldehyde (CA) may contribute to immune function during pathogen infections, and CA has been reported to have positive effects on gut health when used as feed additive for livestock. Here, we investigated whether CA could enhance antibody production and specific immune responses during infection with an enteric ...
Williams, Andrew Richard   +6 more
openaire   +3 more sources

The Relationship between Circulating Antibodies and Immunity to Helminthic Infections

1970
Publisher Summary This chapter demonstrates the protective effect of humoral antibodies for helminthic infections that have been put into hosts other than the normal species. The results obtained under these conditions are better than those occuring in the normal host–parasite systems; this suggests that the antibodies have a part to play in ...
openaire   +2 more sources

In vitro parasite antigen-induced antibody responses in human helminth infections.

The Journal of Immunology, 1985
Abstract Helminth parasites characteristically induce vigorous antibody responses in human infections, but the immunoregulatory mechanisms determining the level of these responses are not at all understood. To investigate these mechanisms, peripheral blood mononuclear cells were obtained from 10 patients with parasitic helminth ...
T B, Nutman, A S, Withers, E A, Ottesen
openaire   +2 more sources

IMMUNOFLUORESCENT LOCALIZATION OF INTERMEDIATE FILAMENTS (IFs) IN HELMINTHS USING ANTI-MAMMALIAN IFs MONOCLONAL ANTIBODY

Journal of Parasitology, 2000
Intermediate filaments (IFs) make up the cytoskeleton of most eukaryotic cells. In vertebrates, a number of IF proteins have been identified, showing distributions unique to tissue or cell type. Information on helminth IFs is limited to some nematode species.
H, Sato, H, Kamiya
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Antibody response to Schistosoma haematobium and other helminth species in malaria-exposed populations from Burkina Faso

Acta Tropica, 2020
Infection with helminths in sub-Saharan Africa could modulate the immune response towards Plasmodium falciparum as well as susceptibility to malaria infection and disease. The aim of this study is to assess the antibody responses to helminths species in malaria-exposed populations from Burkina Faso.
Mangano V. D.   +9 more
openaire   +4 more sources

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