Results 41 to 50 of about 64,981 (166)

Humanized Antibodies. Modern Developments and Prospects for the Creation of Medical Protectors Against Biological Threads and Hazards

Вестник войск РХБ защиты
Passive immunization is the variant of the immunization, in which antibodies are introduced into the body in quantities, sufficient to provide a therapeutic effect.
A. S. Gorshkov, D. V. Pechenkin, A. V. Kuznetsovskiy, D. V. Borovskoy   +3 more
doaj   +1 more source

Application of Genetically-Engineered Anti-CEA Antibodies for Potential Immunotherapy of Colorectal Cancer

The International Journal of Biological Markers, 1992
Hitherto anti-CEA monoclonal antibodies (MAbs), normally of mouse origin, have been used primarily for clinical diagnosis of colorectal cancer, either as a tumor marker in serum to monitor tumor recurrence, or latterly as a means to localize in vivo CEA ...
N. Hardman, B. Murray, M. Zwickl, F. Kolbinger, G. Pluschke   +4 more
doaj   +1 more source

Radiopharmaceuticals in immunoscintigraphy and radioimmunotherapy

Nucleus, 2012
The high morbidity-mortality of cancer makes this condition in Cuba, and at international level, a serious health problem. Radioimmunodiagnosis and radioimmunotherapy based in the growing biotechnological advances, and the actual knowledge of molecular
René Leyva Montaña
doaj  

Anticuerpos monoclonales. Aspectos básicos

Neurología, 2011
Resumen: Introducción: Los anticuerpos monoclonales son una poderosa herramienta para el diagnóstico de laboratorio y un instrumento cada vez más utilizado en el tratamiento de diversas enfermedades.
A. García Merino
doaj   +1 more source

Monoclonal antibodies. Basic features

Neurología (English Edition), 2011
Introduction: Monoclonal antibodies are a powerful tool in laboratory diagnosis and are increasingly used in the treatment of several diseases. Development: Antibody development and characterization has a long history and goes back to immunology itself ...
A. García Merino
doaj   +1 more source

Passive immunotherapy for Alzheimer’s disease: challenges & future directions

Journal of Translational Medicine
Passive immunotherapy with specific antibodies targeting Amyloid β (Aβ) peptide or tubulin-associated unit (tau) protein has emerged as a promising therapeutic approach in Alzheimer’s disease (AD).
Ling Xiao Yi, Eng King Tan, Zhi Dong Zhou   +2 more
doaj   +1 more source

Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer’s disease (BLAZE)

Alzheimer’s Research & Therapy, 2018
Background We investigated the effect of crenezumab, a humanized anti-amyloid-beta (Aβ) immunoglobulin (Ig)G4 monoclonal antibody, on biomarkers of amyloid pathology, neurodegeneration, and disease progression in patients with mild-to-moderate Alzheimer ...
Stephen Salloway, Lee A. Honigberg, William Cho, Michael Ward, Michel Friesenhahn, Flavia Brunstein, Angelica Quartino, David Clayton, Deborah Mortensen, Tobias Bittner, Carole Ho, Christina Rabe, Stephen P. Schauer, Kristin R. Wildsmith, Reina N. Fuji, Shehnaaz Suliman, Eric M. Reiman, Kewei Chen, Robert Paul   +18 more
doaj   +1 more source

Humanized monoclonal antibodies

, 2023
Humanized monoclonal antibodies.
openaire   +1 more source

APPLICATION OF GENE ENGINEERING IN THE TREATMENT OF PATIENTS WITH COVID-19

Медична наука України
Background. Modern therapeutic options for the treatment of COVID-19 combine the use of drugs that affect both the virus itself and the components of the body's immune response.
V.D. Moskaliuk, I.V. Balaniuk, S.R. Melenko, Yu.O. Randiuk   +3 more
doaj   +1 more source

A Systemically Administered Humanized Anti-Nav1.7 Antibody with Long-Lasting Analgesic Activity and Preserved Physiological Nociception

Pharmaceutics
Background: Neuropathic pain remains difficult to treat because current analgesics often provide insufficient efficacy or dose-limiting adverse effects.
Sosuke Yoneda, Daisuke Uta, Kana Yasufuku, Takuya Yamane, Saho Yoshioka, Keiko Takasu, Takaya Izumi, Sayaka Fujita, Daiki Nakamori, Shiori Kawasaki, Tatsuya Takahashi, Mai Yoshikawa, Koichi Ogawa, Erika Kasai   +13 more
doaj   +1 more source