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Bispecific antibodies for viral immunotherapy [PDF]
Human Vaccines & Immunotherapeutics, 2017 Bispecific antibody engineering, in which binding specificities toward 2 distinct epitopes are combined into a single molecule, can greatly enhance immunotherapeutic properties of monoclonal antibodies.
Elisabeth K. Nyakatura +2 more
doaj +3 more sources
VIRAL ANTIBODIES IN PRESCHOOL CHILDREN [PDF]
Iranian Journal of Public Health, 1974 One hundred sera from children 1 - 6 years of age, representative of a large serum collection, were tested for the prevalence of antibodies against different viruses.
S. Saidi
doaj +3 more sources
A potent Gc neutralizing antibody reveals architecture-dependent bispecific protection against SFTSV [PDF]
Emerging Microbes and InfectionsSevere fever with thrombocytopenia syndrome virus (SFTSV) is an emerging bunyavirus that causes severe fever with thrombocytopenia syndrome (SFTS), with a mortality rate of up to 30%. Currently, there are no approved vaccines or therapeutics for clinical
Hongjie Lu +20 more
doaj +2 more sources
Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities. [PDF]
PLoS PathogensThe receptor-binding protein of influenza A virus, hemagglutinin (HA), is the most abundant protein on the viral surface. While high densities of HA are thought to improve cellular attachment by increasing avidity for the viral receptor, they may also ...
Ananya Benegal +5 more
doaj +2 more sources
Antibodies targeting HSV glycoprotein B require effector functions to protect neonatal mice [PDF]
Journal of VirologyGlycoprotein B (gB) serves as the viral fusion protein for herpes simplex virus (HSV), mediating fusion between viral and host membranes resulting in infection.
Matthew D. Slein +8 more
doaj +2 more sources
Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]
, 2013 Background: HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...
Briggs, David, Dr. +11 more
core +18 more sources
Platelet antibodies in viral hepatitis
The Turkish Journal of Pediatrics, 1987 O Hasdal, S Ozsoylu, N Koçak
doaj +2 more sources
Viral antibodies in multiple sclerosis [PDF]
The Italian Journal of Neurological Sciences, 1982 The sera of 176 MS patients and of 150 healthy adult controls were assayed for antibodies against mumps, rubella, Sendai and herpes simplex viruses, a higher prevalence of measles c.f.a. having already been demonstrated in the MS patients. The CSF of 48 of the MS patients were subjected to the same tests.
Ferrante, P. +3 more
openaire +2 more sources
Viral antibodies in infectious mononucleosis [PDF]
FEMS Immunology & Medical Microbiology, 1994 Patients with Epstein-Barr virus (EBV) infectious mononucleosis (IM) usually develop heterophilic antibodies and some autoantibodies. Antibodies to rubella, measles, adeno-, entero-, herpes simplex, cytomegalo- and varicella-zoster viruses were titrated in sera from IM patients and matched healthy controls using the complement fixation test (CFT) and ...
G, Haukenes +5 more
openaire +3 more sources
Viral Antibodies in Diabetes Mellitus [PDF]
BMJ, 1969 Sera from 123 patients with diabetes mellitus of recent onset, 155 patients with diabetes of more than two years' duration, and 250 normal persons were collected over a period of two and a half years. All sera were tested for neutralizing antibody to Coxsackie virus types B1-6, and a sample was tested for complement-fixing antibody to a number of viral,
D R, Gamble +4 more
openaire +2 more sources