Results 131 to 140 of about 494,114 (145)
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Antibodies sustain viral control
Science, 2016HIV-1 Therapy For many infected individuals, antiretroviral therapy (ART) means that an HIV-1 diagnosis is no longer a death sentence. But the virus persists in treated individuals, and complying with the intense drug regimen to keep virus loads down can be challenging for patients. Seeking an alternative, Byrareddy et al.
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An antibody to block viral fusion [PDF]
Science, 2016 HIV-1 Antibodies A small fraction of HIV-1–infected individuals develop broad and potent antibodies that bind the HIV-1 envelope protein (Env). These antibodies recognize a limited set of conserved epitopes on Env, such as Env's host receptor-binding site. Kong et al.
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Antibody enhanced viral growth in macrophages
Immunology Letters, 1985Antiviral antibody can promote viral entry into macrophages by pathways involving cellular receptors for the Fc portion of immunoglobulin or for complement components. Whether virus taken up through these routes is restricted or results in productive infection depends upon a balance between a number of variables. These include the virus strain and dose,
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Antibody Affinity and Valence in Viral Neutralization
The Journal of Immunology, 1972Abstract This work shows that viral neutralization appears to be a function not only of antibody concentration but also of affinity, valence, and possibly molecular configuration of antibody. When antibody molecules of similar valence are grouped, neutralization increases with increasing molecular affinity.
S E, Blank, G A, Leslie, L W, Clem
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Antibody-Dependent Enhancement of Viral Infectivity
1986Publisher Summary This chapter surveys the historical background to the phenomenon of antibody-dependent enhancement (ADE) of viral infectivity and considers the two mechanisms that are known to exist. It updates the earlier review of Halstead that was concerned solely with enhancement mediated by cellular receptors for the Fc portion of ...
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Antibodies for the prevention and treatment of viral diseases
Antiviral Research, 2000This paper reviews current use and evolving role of polyclonal and monoclonal antibody products for the prevention and treatment of viral diseases. Antibodies continue to be indicated for prophylaxis either prior to an anticipated exposure especially in situations of travel, or more commonly following an exposure.
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Detection of Viral Antigens and Antibodies
1989Serological techniques have been the most widely used means of diagnosing viral diseases for years, but several of their shortcomings have shifted the emphasis toward the direct detection of antigens. Nevertheless, serological testing is still useful if it is impractical or impossible to demonstrate the presence of a viral antigen, e.g., measles virus,
Edouard Kurstak +5 more
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VIRAL ANTIBODIES IN THYROTOXICOSIS
The Lancet, 1975A. Joasoo, P. Robertson, I.P.C. Murray
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VIRAL ANTIBODIES AND BRONCHIAL CARCINOMA
The Lancet, 1977M E Hodson +3 more
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Use of Monoclonal Antibodies for Viral Diagnosis
1983The performance characteristics of immunoassay systems are dependent to extent on the binding characteristics of the immunoreactants utilized. For this investigators involved in the use of immunoassay systems for the detection of bial antigens have been particularly interested in the evolving technology re] the production and development of monoclonal ...
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