Results 171 to 180 of about 955,307 (300)

Antibody-dependent viral infection in macrophages.

Uirusu, 1989
H, Ochiai, M, Kurokawa
openaire   +3 more sources

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Potent <i>in vitro</i> synergistic antiviral effects of the pan-coronavirus fusion inhibitor EK1 in combination with RBD-specific antibodies or M^pro inhibitors. [PDF]

J Virol
Xiu R, Wang Y, Cai W, Wang Q, Xie M, Wang Y, Li C, Wang Q, Huang J, Ying T, Song C, Lu L, Jiang S, Xu W.   +13 more
europepmc   +1 more source

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]

, 2017
Diamond, Michael S, et al,, Fox, Julie M, Sukulpovi-Petty, Soila   +3 more
core   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Poxvirus A52 protein subverts autophagy flux by blocking autophagosome-lysosome fusion to promote viral replication. [PDF]

PLoS Pathog
Niu K, Fang Y, Deng Y, Wang Z, Xie S, Zhu J, Song B, Wu W, Jing Z, Peng C.   +9 more
europepmc   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Exosomes in meconium mediate horizontal transmission and immune evasion of reticuloendotheliosis virus. [PDF]

Virol J
Fu Z, Geng R, Ren Z, Cui W, Wang Y, Chang S, Zhao P.   +6 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Discovery of actinators, actin-derived bioactive peptides that modulate cytoskeleton and actin-related cellular activities. [PDF]

Sci Adv
Yi F, Guo J, Vo TT, Hetrick B, Haikerwal A, Zhou Z, Sealey L, He S, Han Y, Chilin L, Spear M, Yu D, Kim Y, Kashanchi F, Zhou T, Xu X, Lockhart C, Wu Y.   +17 more
europepmc   +1 more source