Results 191 to 200 of about 955,307 (300)

Host Immune Response Mechanisms Against Herpes Simplex Virus Type 2 Infection. [PDF]

Pathogens
Mei Y, Teng H, Wang J.
europepmc   +1 more source

[Bacterial and viral antibodies in human immunoglobulin preparations. II. Viral antibodies].

Medycyna doswiadczalna i mikrobiologia, 1979
H, Albrycht, T, Wysokińska, D, Imbs, Z, Sporzyńska, B, Bucholc   +4 more
openaire   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Building better antibody responses: The interplay of infection, vaccination, and immune imprinting. [PDF]

PNAS Nexus
Carissa Aurelia L, Selva KJ, Chung AW.
europepmc   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

A visible assay for evaluating the inhibitory activity of drug and antibody against HBV infection. [PDF]

Microbiol Spectr
Yan H, Li Y, Liu C, Guo H, Liu Y, Wang H, Ge X, Zhang Z, Ju B.   +8 more
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Chicken infectious anemia virus exploits host CK2α as an essential factor for its replication via VP2 Ser182/Asp183-mediated interaction. [PDF]

J Virol
Ma Z, Wang H, Wang Y, Li X, Cao H, Gao L, Zheng SJ.   +6 more
europepmc   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Impact of maternal antibodies and weaning stress on the replication and transmission of human H3N2 influenza A in piglets. [PDF]

J Virol
Ciacci Zanella G, Cardenas MI, Hutter CR, Snyder CA, Wymore Brand M, Arruda B, Perez DR, Anderson TK, Rajão DS, Baker AL.   +9 more
europepmc   +1 more source