Results 201 to 210 of about 2,860,326 (352)

Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications

Advanced Healthcare Materials, EarlyView.
Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho, Yunyoung Choi, Yerim Jang, Hyejeong Seong   +3 more
wiley   +1 more source

Design and Analysis of Novel HEV Vaccine Variants and Evaluation of Two Selected Candidates in a Porcine Infection Model. [PDF]

Liver Int
Hrabal I, Aliabadi E, Weber S, Ssebyatika GL, Krey T, Holicki CM, Schmid L, Dinkelborg K, Schröder C, Fast C, Behrendt P, Groschup MH, Eiden M.   +12 more
europepmc   +1 more source

Fluid Shear‐Controlled Pro/Anti‐Inflammatory Osteomodulatory Construct for Drug‐Free Immune Activation Through Cationic Ion Channel Activation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed PCL scaffold coated with Arginine was laminated with electrospun polyvinyl alcohol (PVA) nanofibers containing cationic cellulose nanocrystals (PVA@cCNC). This created nanoisland‐like regions of aligned and random cCNC‐rich fibers. The composite scaffold, under fluid shear stimulation, modulated macrophage polarization from M1 to M2 ...
Keya Ganguly, Aayushi Randhawa, Sayan Deb Dutta, Jieun Lee, Youjin Seol, Mehran Mohammad Hossein Pour, Tejal V. Patil, Rumi Acharya, Ki‐Taek Lim   +8 more
wiley   +1 more source

Integration of biomimetic organoid-on-chip and 2D models advances the mechanistic Understanding of STEAP3-mediated regulation in intestinal viral infection. [PDF]

Sci Rep
Chen YW, Chiang HJ, Liu KT, Kao CW, Xie SR, Su CM, Shih YY.   +6 more
europepmc   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Understanding the Enigmatic Dance of Immune-Mediated Viral Infections and Their Pathogenetic Mechanisms. [PDF]

Vet Med Sci
Karabulut MC, Oğuzoğlu TÇ.
europepmc   +1 more source

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

Nature, 2021
Tyler N. Starr, N. Czudnochowski, Zhuoming Liu, F. Zatta, Young-Jun Park, A. Addetia, D. Pinto, M. Beltramello, P. Hernandez, Allison J. Greaney, R. Marzi, W. Glass, Ivy Zhang, A. Dingens, John E. Bowen, M. A. Tortorici, A. Walls, Jason A. Wojcechowskyj, A. De Marco, Laura E. Rosen, Jiayi Zhou, Martin Montiel-Ruiz, Hannah Kaiser, J. Dillen, H. Tucker, J. Bassi, C. Silacci-Fregni, M. P. Housley, J. di Iulio, Gloria Lombardo, Maria L. Agostini, Nicole Sprugasci, K. Culap, S. Jaconi, M. Meury, Exequiel Dellota Jr, R. Abdelnabi, S. Foo, E. Cameroni, S. Stumpf, T. Croll, J. Nix, C. Havenar-Daughton, L. Piccoli, F. Benigni, J. Neyts, A. Telenti, Florian A. Lempp, M. Pizzuto, J. Chodera, C. Hebner, H. Virgin, S. Whelan, D. Veesler, D. Corti, J. Bloom, G. Snell   +56 more
semanticscholar   +1 more source

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

Advanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim, Inhyuk Hwang, Juhee Seo, Chaiwon Kim, In‐Jeong Choi, Miran Kang, Min‐Seok Rha, Youngjae Hong, Jooyoung Kim, Seung‐Ki Baek, Jung‐Hwan Park, Hyung‐Ju Cho, Kihyuck Kwak   +12 more
wiley   +1 more source

Insights into the Landscape of Alphavirus Receptor and Antibody Interactions. [PDF]

Viruses
Poudyal S, Bandyopadhyay A, Kuhn RJ.
europepmc   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source