Results 201 to 210 of about 950,836 (305)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Co-Circulation of Tick-Borne <i>Bandaviruses</i> and <i>Orthonairoviruses</i> Across Humans, Livestock, and Rats in Pakistan: Serologic Evidence and Public Health Implications. [PDF]

Viruses
Ammar M, Chen S, Saqib M, Zhang J, Sial AU, Zia A, Fang Y, Mansoor MK, Moming A, Shahzad A, Hafeez R, Javed A, Hassan A, Hu B, Zohaib A, Shen S, Deng F.   +16 more
europepmc   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

The porcine reproductive and respiratory syndrome [PDF]

, 1993
Albina, E., Benfield, D., Conzelmann, Karl-Klaus, Drew, T. W., Meulenberg, J. J. M., Murtaugh, M., Nelson, E. A., Thiel, Heinz-Jürgen, Wensvoort, G.   +8 more
core   +1 more source

Under the Radar: Immune Evasion, Pathogenesis and Control of HIV Infection. [PDF]

Int J Mol Sci
Tarrés-Freixas F, Trinité B, Carrillo J, Blanco J.   +3 more
europepmc   +1 more source

Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This work demonstrates the design, fabrication, and the first‐time test of a 2D photonic crystal surface for photonic resonator absorption microscopy. The designed surface uniformly enhances electromagnetic near fields, achieving > 100% improved detecting uniformity for surface‐captured AuNPs from a blocking biosensor assay aimed for detecting SARS‐CoV‐
Weinan Liu, Siyan Li, Edmond Chow, Seemesh Bhaskar, Ying Fang, Brian T. Cunningham   +5 more
wiley   +1 more source

Avian Immunoglobulin Y Antibodies Targeting the Protruding or Shell Domain of Norovirus Capsid Protein Neutralize Norovirus Replication in the Human Intestinal Enteroid System. [PDF]

Vaccines (Basel)
Xia M, Ichou M, Landivar M, Zhou P, Vadlamudi SN, Leruth A, Nyblade C, Cox P, Yuan L, Goepp J, Tan M.   +10 more
europepmc   +1 more source

Sialic Acid Sensing via Molecularly Imprinted Polymer on Laser‐Induced Graphene

Advanced Sensor Research, EarlyView.
Sialic acid is an important biomarker for oral and overall health. Salivary levels of sialic acid are linked with oral cancer and other diseases. We develop a point‐of‐care sensor for sialic acid, based on molecularly imprinted aminophenylboronic acid electropolymerized onto laser‐induced graphene.
Alexander V. Shokurov, Max Nobre Supelnic, Carlo Menon   +2 more
wiley   +1 more source

Efficacy of a Modified-Live Virus Combination Vaccine (CDV, CAV, CPV, CPiV), Canigen^TM DHPPi, in Puppies Vaccinated at Six Weeks of Age. [PDF]

Viruses
Loukeri S, Senseby F, Benizeau E, Cronier J, Gueguen S.   +4 more
europepmc   +1 more source