Nipah Virus Antibodies in Bats, the Philippines, 2013-2022. [PDF]
Kaku Y+22 more
europepmc +1 more source
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]
Diamond, Michael S+3 more
core +1 more source
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang+10 more
wiley +1 more source
Antigenic and mutational insights into the Nipah virus G glycoprotein: implications for viral entry, host specificity, therapeutics, and vaccine development. [PDF]
Mohamad Nasir NS+7 more
europepmc +1 more source
Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost+9 more
wiley +1 more source
The neonatal Fc receptor (FcRn): Guardian or Trojan Horse in viral infection? [PDF]
Na L, Zheng Y, Yang JB, Bao HL, Tang YD.
europepmc +1 more source
Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler+4 more
wiley +1 more source
Tiantan vaccinia virus-based vaccine with promising safety provides sustained protection against mpox in non-human primates. [PDF]
Zhu L+19 more
europepmc +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Inhaled bispecific single-domain antibody BM219 for mild-to-moderate COVID-19: a double-blind, randomized, placebo-controlled phase 2 trial. [PDF]
Wu Y+12 more
europepmc +1 more source