Results 281 to 290 of about 2,860,326 (352)

Optimizing the breadth of SARS-CoV-2-neutralizing antibodies in vivo and in silico. [PDF]

Hum Vaccin Immunother
Kuroda D, Moriyama S, Sasaki H, Takahashi Y.   +3 more
europepmc   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Future of bNAbs in HIV Treatment. [PDF]

Curr HIV/AIDS Rep
Tebas P.
europepmc   +1 more source

Enhanced Doxorubicin Cytotoxicity on Breast Cancer Spheroids by Aptamer Targeted Co‐Delivery with Hyaluronidase

Advanced Therapeutics, EarlyView.
Breast cancer is one of the most prevalent solid tumors in women. Doxorubicin is loaded mesoporous silica nanoparticles, capped with HER2‐specific aptamers, and the particle surface is functionalized with hyaluronidase. This dual‐functionalized nanocarrier system offers a promising solution for the drug resistance by solid tumors.
Murat Kavruk, Dide Su Demirel, Farzaneh Bonyadi, Buket Çakmak Güner, Ali Doğan Dursun, Cekdar Vakifahmetoglu, Bilge Güvenç Tuna, Uğur Şahin, Veli Cengiz Ozalp   +8 more
wiley   +1 more source

Non-cognate ligands of hepatitis C virus envelope broadly neutralizing antibodies induce virus-neutralizing sera in mice. [PDF]

Front Immunol
Walimbwa SI, Bharadwaj S, Kosztyu P, Vankova L, Kuchar M, Kopecna E, Effenberg R, Drasar L, Raskova Kafkova L, Maly P, Raska M.   +10 more
europepmc   +1 more source

Genetic Engineering Methods in Primary T Cells

Advanced Therapeutics, EarlyView.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source

Polyclonal LC3B Antibodies Generate Non-Specific Staining in the Nucleus of Herpes Simplex Virus Type 1-Infected Cells: Caution in the Interpretation of LC3 Staining in the Immunofluorescence Analysis of Viral Infections. [PDF]

Int J Mol Sci
Ripa I, Andreu S, Galdo D, Caballero O, Bello-Morales R, López-Guerrero JA.   +5 more
europepmc   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

National representative seroprevalence of viral hepatitis B, C, and D seromarkers in Ukraine, 2021. [PDF]

Euro Surveill
Kasatkina L, Fedorchenko V, Sidorova I, Gomenyuk L, Yakovets O, Brandl M, Ivanchuk I, Dudareva S, Nesterova O.   +8 more
europepmc   +1 more source