Results 91 to 100 of about 2,598,104 (298)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
An Immunoperoxidase Monolayer Assay (IPMA) for the detection of lumpy skin disease antibodies.
, 2020 During this study a new Immunoperoxidase Monolayer Assay (IPMA) was developed for the detection of antibodies against lumpy skin disease virus (LSDV) in an easy and low tech setting.
M. Vastag +6 more
core +1 more source
Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]
, 2014 Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Lucocq, John Milton, Griffiths, Gareth
core +1 more source
Nature Communications, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Chang-Han Lee +18 more
doaj +1 more source
Antibody Engineering for the Development of Therapeutic Antibodies
Molecules and Cells, 2005 Therapeutic antibodies represent one of the fastest growing areas of the pharmaceutical industry. There are currently 19 monoclonal antibodies in the market that have been approved by the FDA and over 150 in clinical developments. Driven by innovation and technological developments, therapeutic antibodies are the second largest biopharmaceutical ...
Sang Jick, Kim +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Expression of recombinant multi-coloured fluorescent antibodies in
, 2011 Background Antibody-fluorophore conjugates are invaluable reagents used in contemporary molecular cell biology for imaging, cell sorting and tracking intracellular events.
Durvasula, Ravi V. +26 more
core +1 more source
Nature Communications, 2019 Lee et al. report an engineered IgG1 Fc domain that behaves like an hFcRn binding pH toggle switch. The authors show that this new half-life extension Fc domain confers improved pharmacokinetics in new humanized knock-in mouse strains that recapitulate ...
Chang-Han Lee +18 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
MULTIPLEX TISSUE ANALYSIS OF NEURONAL LINEAGE MARKERS IN DEVELOPING MOUSE BRAIN
IBRO Neuroscience Reports, 2023 Eugenia Kuteeva, Mikael Malmqvist
doaj +1 more source