Results 231 to 240 of about 84,266 (263)

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

EGFR- and HER3-targeted bispecific antibody-drug conjugate demonstrates antitumor activity in metastatic castration-resistant prostate cancer. [PDF]

J Clin Invest
Fang B, Li X, Lu Y, Ma W, Gan H, Zhang T, Liu Q, Wang B, Wang Z, Zhu Y, Zhu H, Xiao S, Bian X, Wei G, Ye D, Zhu Y.   +15 more
europepmc   +1 more source

Efficacy and safety of antibody-drug conjugates in the treatment of non-small cell lung cancer: a systematic review and meta-analysis of prospective clinical trials

Xiaoni Jin, Weixing Zhao, Bo Li, Yujia Gu, Zirui Li, Wanjing Guo, Xinxin Lü, Jun Jiang   +7 more
openalex   +1 more source

Ultra‐High‐Throughput Discovery of Multifunctional Polyphenolic Coatings on Droplet Microarrays

Advanced Materials, EarlyView.
An ultra‐high‐throughput (UHT) combinatorial strategy enables the miniaturized synthesis and screening of ≈30 000 polyamine‐polyphenolic (PaPp) coatings using droplet microarrays (DMA). This approach reveals hundreds of previously unknown fluorescent, redox‐active, and antibacterial materials, including multifunctional, cell‐compatible surfaces ...
Vania Tanda Widyaya, Joaquín E. Urrutia Gómez, Paul Reuß, Alexander Welle, Rolf A. Gattung, Jana Mayer, Peter Krolla, Markus Reischl, Pascal Friederich, Anna A. Popova, Thomas Schwartz, Pavel A. Levkin   +11 more
wiley   +1 more source

Rational payload selection enables high antitumoral efficacy of an anti-EGFR antibody-drug conjugate against ovarian tumors. [PDF]

Neoplasia
Almaraz-Postigo S, Redondo-Puente M, Pandiella A.   +2 more
europepmc   +1 more source

Population-Based Modeling to Predict Human PK/PD of TAK-500, an Anti-CCR2 Antibody-Drug Conjugate for First-in-Human Study in Cancer Patients. [PDF]

Clin Transl Sci
Saravanakumar A, Deng R, Dong L, Haridas S, Xia CQ, Appleman VA, Abu-Yousif AO, Piatkov K, Wang H.   +8 more
europepmc   +1 more source

Correction: Harnessing ExDNA for precision Exatecan delivery in cancer: a novel antibody-drug conjugate approach. [PDF]

Mol Cancer
Ianniello Z, Lu H, Quijano E, Colón-Ríos DA, Rackear M, Bommireddy V, Ludwig DL, Shen Z, Glazer PM.   +8 more
europepmc   +1 more source

Data from Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody–Drug Conjugates

Saskia Schmitt, Paul Machui, Isabelle Mai, Sarah Herterich, Swetlana Wunder, Philipp Cyprys, Marcus Gerlach, Philipp Ochtrop, Christian P. R. Hackenberger, Dominik Schumacher, Jonas Helma, Annette M. Vogl, Marc‐André Kasper   +12 more
openalex   +1 more source

Antibody-drug conjugate sequencing in HER2-positive metastatic breast cancer: Real-world outcomes of trastuzumab deruxtecan with and without prior T-DM1 exposure. [PDF]

Breast
Kemik F, Şahin TK, Özçelik H, Sezer A, Başaran G, Açıkel Yüksel SD, Güney G, Yıldız İ, Er Ö, Korkmaz T, Biter S, Erdem D, Tünbekici S, Oruç A, Güren AK, Kaban K, Aykan MB, Ekinci ÖB, Deliktaş Onur İ, Kalem A, Altunok O, Seyyar M, Güney B, Akdoğan O, Yazıcı M, Majidova N, Türker S, Köylü B, Kıkılı Cİ, Demir N, Tunalı D, Laçin Ş, Tural D, Bilici A, Bayram E, Göker E, Araz M, Bayoğlu İV, Molinas Mandel N, Karadurmuş N, Çelik E, Ateş Ö, Yeşil Çınkır H, Yılmaz M, Gürsu RU, Yazıcı O, Çabuk D, Güven DC, Selçukbiricik F, Aksoy S, Gündüz Ş.   +50 more
europepmc   +1 more source

Can Epithelial-Myoepithelial Carcinoma of the Breast Benefit from TROP2 Antibody-Drug Conjugate? [PDF]

Onco Targets Ther
Zhao Q, Luo X, Xing H, Jiang C, Ma J, Tang L.   +5 more
europepmc   +1 more source