Results 291 to 300 of about 589,804 (355)

Nanomaterial‐Integrated Fiber Neural Probes for Deep Brain Monitoring and Modulation: Challenges and Opportunities

Advanced Functional Materials, EarlyView.
The article presents nanomaterial‐integrated fiber neural probes as innovative tools for deep brain molecular sensing, neural stimulation, and temperature monitoring. It examines breakthroughs in SERS‐based biomolecule detection, thermoplasmonic activation, and luminescent thermometry, alongside strategies to overcome stability, specificity, and ...
Di Zheng, Yang Li, Muhammad Fayyaz Kashif, Linda Piscopo, Massimo De Vittorio, Ferruccio Pisanello   +5 more
wiley   +1 more source

8C7: A Fully Human Anti-PTGFRN Monoclonal Antibody-Drug Conjugate Inhibiting Tumour Growth of Mesothelioma and Paediatric Medulloblastoma Cell Lines. [PDF]

J Cell Mol Med
Marquez J, Dong J, Yue B, Hayashi J, Dong C, Oshimura M, Serrero G.   +6 more
europepmc   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Preclinical Characterization of XB002, an Anti-Tissue Factor Antibody-Drug Conjugate for the Treatment of Solid Tumors. [PDF]

Mol Cancer Ther
Kantak S, Faggioni R, Cai AG, Bhatti MM, Li J, Vainshtein I, Cheng J, Mendelsohn BA, Gaudreault J, Migone TS, Theunissen JW.   +10 more
europepmc   +1 more source

Advances in Stimuli‐Responsive Organic Materials and Polymers toward Intelligent CO2 Capture

Advanced Functional Materials, EarlyView.
Schematic illustration of the relationship between different stimuli and stimuli‐responsive organic materials and polymers for carbon dioxide (CO2) capture. Main stimuli include redox, pH, magnetism, temperature, light, and pressure. Furthermore, multi‐responsive materials, due to their high adaptability and scalability in complex environments, are ...
Jian Zhou, Marc Deissenroth‐Uhrig, Markus Gallei   +2 more
wiley   +1 more source

Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody-drug conjugate. [PDF]

Antib Ther
Chang HW, Wang J, Liu H, Xing C, Chen J, Frey G, Boyle WJ, Short JM.   +7 more
europepmc   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

Streamlined High-Throughput Data Analysis Workflow for Antibody-Drug Conjugate Biotransformation Characterization. [PDF]

Anal Chem
Liu K, Ai Y, Tan HY, Yuan J, Meissen JK, Zhang Y, Huang Y, Rosenbaum AI.   +7 more
europepmc   +1 more source

Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications

Advanced Healthcare Materials, EarlyView.
Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho, Yunyoung Choi, Yerim Jang, Hyejeong Seong   +3 more
wiley   +1 more source

Author Correction: Placenta-specific1 (PLAC1) is a potential target for antibody-drug conjugate-based prostate cancer immunotherapy. [PDF]

Sci Rep
Nejadmoghaddam MR, Zarnani AH, Ghahremanzadeh R, Ghods R, Mahmoudian J, Yousefi M, Nazari M, Ghahremani MH, Abolhasani M, Anissian A, Mahmoudi M, Dinarvand R.   +11 more
europepmc   +1 more source