Results 161 to 170 of about 49,422 (253)

Pharmacokinetic and Pharmacodynamic Modeling of Antibody-Drug Conjugates. [PDF]

Cancers (Basel)
Glassman PM.
europepmc   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

Advanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed, Zeeshan Tahir, Fahri Alkan, Yavuz Nuri Ertas   +3 more
wiley   +1 more source

The role of antibody-drug conjugates in the treatment of lung cancer. [PDF]

Front Oncol
Zlatanova T, Changalova A, Janzic U.
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Exatecan Payload-Based Antibody-Drug Conjugates with a Short Hydrophilic Cleavable Linker. [PDF]

ACS Med Chem Lett
Jammalamadaka V, Liu J, Bhakta S, Velupula S, Martha B, Jonnalagadda V, Junutula JR.   +6 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Deruxtecan-based antibody-drug-conjugates induce senescence in HER2-positive breast cancer. [PDF]

Sci Rep
Vezzoli E, Pinos R, Galbiati S, Zambroni D, Dall'Ara C, Locatelli A, Colombo E, Galbardi B, Viganò L, Lavagnino Z, Scielzo C, De Palma C, Bianchini G, Tacchetti C, Daniele T.   +14 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Multi-payload antibody-drug conjugates for photothermal dynamic and chemotherapy of HER2-positive breast cancer. [PDF]

Mater Today Bio
Zhang Y, Bai Y, Ren X, Fan Y, Lv Z, Song Q, Wang X, Shi H.   +7 more
europepmc   +1 more source