Editorial: Repurposing cancer immunotherapies for use in autoimmunity and transplantation. [PDF]
Boardman DA, Smyth LA, Ferreira LMR.
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Infant CD4 T-Cell Response to SARS-CoV-2 mRNA Vaccination Is Restricted in Cytokine Production and Modified by Vaccine Manufacturer. [PDF]
Peters MQ +12 more
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Exploring the role of APRIL in autoimmunity: implications for therapeutic targeting in systemic lupus erythematosus, rheumatoid arthritis, and Sjögren's syndrome. [PDF]
Poznyak AV +7 more
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Role of tertiary lymphoid structures in the tumour microenvironment and immunotherapy response of renal cell carcinoma. [PDF]
Yang L +9 more
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Pidotimod alleviated experimental autoimmune encephalomyelitis by regulating the balance of splenic lymphocytes. [PDF]
Wang Y +13 more
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Review: radiotherapy-mediated B cells within the TLS influence the tumor microenvironment. [PDF]
Yang H +7 more
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Plaque Formation in Agar by Single Antibody-Producing Cells
Science, 1963Distinct plaques, each of which is due to the release of hemolysin by a single antibody-forming cell, are revealed by complement after incubation, in an agar layer, of a mixture of sheep red cells and lymphoid cells from a rabbit immunized with sheep red
N. K. Jerne, A. Nordin
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Antibody-Producing Cells in Division
Science, 1967Cells producing antibody were detected by a modified Jerne plaque technique. Of plaques initially containing a single central cell, 2.6 percent (45/1742) later had two. Mitosis of cells producing antibody was directly observed, with a mitotic time of not less than 40 minutes for the one mitosis timed at 37°C.
Alice J. Claflin, Oliver Smithies
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Antibody-producing cells in human periapical granulomas and cysts
Journal of Endodontics, 1981Immunoglobulin-producing cells were quantitated in 20 human periapical granulomas and cysts. Results showed that 42% of the lymphoid cells comprising 19% of all inflammatory cells contained immunoglobulins. The majority of lymphocytes (81%) were not associated with immunoglobulin production. IgG was found in 74%, IgA in 20%, IgE in 4%, and IgM in 2% of
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