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Antibody-Producing Cells in Division
Science, 1967Cells producing antibody were detected by a modified Jerne plaque technique. Of plaques initially containing a single central cell, 2.6 percent (45/1742) later had two. Mitosis of cells producing antibody was directly observed, with a mitotic time of not less than 40 minutes for the one mitosis timed at 37°C.
A J, Claflin, O, Smithies
exaly +3 more sources
Immunocytochemical localization of antibody-producing cells in adult lamprey
Immunology Letters, 1983Antibody-producing cells were localized in the fat column of adult lamprey previously immunized with 'O'RBC. These cells were visualized using rabbit anti-lamprey antibody antiserum in the peroxidase anti-peroxidase (PAP) immunocytochemical technique.
M F Filosa, John H Youson
exaly +3 more sources
Plaque Formation in Agar by Single Antibody-Producing Cells
Science, 1963Distinct plaques, each of which is due to the release of hemolysin by a single antibody-forming cell, are revealed by complement after incubation, in an agar layer, of a mixture of sheep red cells and lymphoid cells from a rabbit immunized with sheep red cells.
N K, Jerne, A A, Nordin
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Antibody-producing cells in human periapical granulomas and cysts
Journal of Endodontics, 1981Immunoglobulin-producing cells were quantitated in 20 human periapical granulomas and cysts. Results showed that 42% of the lymphoid cells comprising 19% of all inflammatory cells contained immunoglobulins. The majority of lymphocytes (81%) were not associated with immunoglobulin production. IgG was found in 74%, IgA in 20%, IgE in 4%, and IgM in 2% of
M H, Stern +3 more
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Association between Macrophages and Specific Antibody Producing Cells
Nature New Biology, 1971MACROPHAGES are involved in the induction of the immune response to various antigens1,2 and ultrastructural observations suggest a close relationship between macrophages, lymphocytes and a variety of immunocompetent cells3,4, although the antibody specificities of the latter have not been demonstrated.
Miller, H R, Avrameas, S
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Analysis of Immunotoxicity by Enumeration of Antibody‐Producing B Cells
Current Protocols in Toxicology, 2006AbstractThe plaque‐forming cell (PFC) assay measures the humoral immune response mediated by the concerted actions of antigen‐presenting cells, T lymphocytes, and B lymphocytes. The most common form of the plaque method is used for the detection of murine primary IgM antibodies directed against the T cell–dependent sheep red blood cell (sRBC) surface ...
Stacey E, Anderson +2 more
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Studies on antibody-producing cells. I. Ultrastructure of 19S and 7S antibody-producing cells.
The Journal of experimental medicine, 1972Antibody-bearing cells of spleen and lymph node of the mouse and rabbit detected by rosette formation with the antigenic red blood cells were collected by micropipet and studied by electron microscopy. More than 300 such cells were examined. In the lymph nodes, rosette-forming cells were all in the lymphocytic and plasmacytic categories.
Gudat, F G +3 more
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